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Caspase-independent Cell Killing by Fas-associated Protein with Death Domain

The binding of Fas ligand to Fas recruits caspase 8 to Fas via an adaptor, FADD/MORT1, and activates a caspase cascade leading to apoptosis. Here, we describe a human Jurkat-derived cell line (JB-6) that is deficient in caspase 8. This cell line was resistant to the apoptosis triggered by Fas engage...

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Detalles Bibliográficos
Autores principales:	Kawahara, Atsuo, Ohsawa, Yoshiyuki, Matsumura, Hirotaka, Uchiyama, Yasuo, Nagata, Shigekazu
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1998
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133085/ https://www.ncbi.nlm.nih.gov/pubmed/9832562

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