The Zinc Finger Protein A20 Inhibits TNF-induced NF-κB–dependent Gene Expression by Interfering with an RIP- or TRAF2-mediated Transactivation Signal and Directly Binds to a Novel NF-κB–inhibiting Protein ABIN

The zinc finger protein A20 is a tumor necrosis factor (TNF)– and interleukin 1 (IL-1)-inducible protein that negatively regulates nuclear factor-kappa B (NF-κB)–dependent gene expression. However, the molecular mechanism by which A20 exerts this effect is still unclear. We show that A20 does not in...

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Detalles Bibliográficos
Autores principales: Heyninck, Karen, De Valck, Dirk, Berghe, Wim Vanden, Van Criekinge, Wim, Contreras, Roland, Fiers, Walter, Haegeman, Guy, Beyaert, Rudi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133159/
https://www.ncbi.nlm.nih.gov/pubmed/10385526

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