Integrin-mediated Activation of Focal Adhesion Kinase Is Required for Signaling to Jun NH(2)-terminal Kinase and Progression through the G1 Phase of the Cell Cycle

The extracellular matrix exerts a stringent control on the proliferation of normal cells, suggesting the existence of a mitogenic signaling pathway activated by integrins, but not significantly by growth factor receptors. Herein, we provide evidence that integrins cause a significant and protracted...

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Detalles Bibliográficos
Autores principales: Oktay, Maja, Wary, Kishore K., Dans, Michael, Birge, Raymond B., Giancotti, Filippo G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133163/
https://www.ncbi.nlm.nih.gov/pubmed/10385525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133163/
https://www.ncbi.nlm.nih.gov/pubmed/10385525

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