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Integrin-mediated Activation of Focal Adhesion Kinase Is Required for Signaling to Jun NH(2)-terminal Kinase and Progression through the G1 Phase of the Cell Cycle
The extracellular matrix exerts a stringent control on the proliferation of normal cells, suggesting the existence of a mitogenic signaling pathway activated by integrins, but not significantly by growth factor receptors. Herein, we provide evidence that integrins cause a significant and protracted...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1999
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133163/ https://www.ncbi.nlm.nih.gov/pubmed/10385525 |