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Domains of Axin Involved in Protein–Protein Interactions, Wnt Pathway Inhibition, and Intracellular Localization

Axin was identified as a regulator of embryonic axis induction in vertebrates that inhibits the Wnt signal transduction pathway. Epistasis experiments in frog embryos indicated that Axin functioned downstream of glycogen synthase kinase 3β (GSK3β) and upstream of β-catenin, and subsequent studies sh...

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Detalles Bibliográficos
Autores principales: Fagotto, François, Jho, Eek-hoon, Zeng, Li, Kurth, Thomas, Joos, Thomas, Kaufmann, Christine, Costantini, Frank
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133179/
https://www.ncbi.nlm.nih.gov/pubmed/10330403

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