CORTIN PROTECTION AGAINST ANAPHYLACTIC SHOCK IN GUINEA PIGS

Studies have been made on a possible protective action of cortin in the prevention of anaphylactic shock induced by crystallized egg albumin. Of sixteen control guinea pigs only two survived. Sixteen of thirty-three cortin-treated animals received hormone at the optimum period of from 2 to 6 hours b...

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Detalles Bibliográficos
Autores principales: Wolfram, J., Zwemer, R. L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1935
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133207/
https://www.ncbi.nlm.nih.gov/pubmed/19870348
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author Wolfram, J.
Zwemer, R. L.
author_facet Wolfram, J.
Zwemer, R. L.
author_sort Wolfram, J.
collection PubMed
description Studies have been made on a possible protective action of cortin in the prevention of anaphylactic shock induced by crystallized egg albumin. Of sixteen control guinea pigs only two survived. Sixteen of thirty-three cortin-treated animals received hormone at the optimum period of from 2 to 6 hours before the shocking dose. Nine survived and two others showed some protection. In groups treated at other time intervals the evidence of protection is inconclusive. 2 weeks after the first test the cortin-treated survivors succumbed to a second antigen dose, which was not preceded by cortical extract.
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spelling pubmed-21332072008-04-18 CORTIN PROTECTION AGAINST ANAPHYLACTIC SHOCK IN GUINEA PIGS Wolfram, J. Zwemer, R. L. J Exp Med Article Studies have been made on a possible protective action of cortin in the prevention of anaphylactic shock induced by crystallized egg albumin. Of sixteen control guinea pigs only two survived. Sixteen of thirty-three cortin-treated animals received hormone at the optimum period of from 2 to 6 hours before the shocking dose. Nine survived and two others showed some protection. In groups treated at other time intervals the evidence of protection is inconclusive. 2 weeks after the first test the cortin-treated survivors succumbed to a second antigen dose, which was not preceded by cortical extract. The Rockefeller University Press 1935-01-01 /pmc/articles/PMC2133207/ /pubmed/19870348 Text en Copyright © Copyright, 1935, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Wolfram, J.
Zwemer, R. L.
CORTIN PROTECTION AGAINST ANAPHYLACTIC SHOCK IN GUINEA PIGS
title CORTIN PROTECTION AGAINST ANAPHYLACTIC SHOCK IN GUINEA PIGS
title_full CORTIN PROTECTION AGAINST ANAPHYLACTIC SHOCK IN GUINEA PIGS
title_fullStr CORTIN PROTECTION AGAINST ANAPHYLACTIC SHOCK IN GUINEA PIGS
title_full_unstemmed CORTIN PROTECTION AGAINST ANAPHYLACTIC SHOCK IN GUINEA PIGS
title_short CORTIN PROTECTION AGAINST ANAPHYLACTIC SHOCK IN GUINEA PIGS
title_sort cortin protection against anaphylactic shock in guinea pigs
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133207/
https://www.ncbi.nlm.nih.gov/pubmed/19870348
work_keys_str_mv AT wolframj cortinprotectionagainstanaphylacticshockinguineapigs
AT zwemerrl cortinprotectionagainstanaphylacticshockinguineapigs

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