THE COLONY MORPHOLOGY OF TUBERCLE BACILLI : I. THE PRESENCE OF SMOOTH COLONIES IN STRAINS RECENTLY ISOLATED FROM SOURCES OTHER THAN SPUTUM

1. Smooth, round, shiny, non-granular, and non-spreading colonies have been observed in cultures of virulent tubercle bacilli freshly isolated from eight human sources other than sputum. The classification of six of these strains as of human type was established by inoculation into rabbits and guine...

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Detalles Bibliográficos
Autor principal: Smithburn, Kenneth C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1935
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133226/
https://www.ncbi.nlm.nih.gov/pubmed/19870367
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author Smithburn, Kenneth C.
author_facet Smithburn, Kenneth C.
author_sort Smithburn, Kenneth C.
collection PubMed
description 1. Smooth, round, shiny, non-granular, and non-spreading colonies have been observed in cultures of virulent tubercle bacilli freshly isolated from eight human sources other than sputum. The classification of six of these strains as of human type was established by inoculation into rabbits and guinea pigs. 2. The 3 per cent NaOH or 6 per cent H(2)SO(4) frequently used in the isolation of tubercle bacilli are definitely unfavorable to the development of smooth colonies. 3. It was observed that smooth colonies are produced in greater number when the pH of the medium (Corper's egg yolk-glycerine) is adjusted to a point near to but slightly on the acid side of neutral.
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spelling pubmed-21332262008-04-18 THE COLONY MORPHOLOGY OF TUBERCLE BACILLI : I. THE PRESENCE OF SMOOTH COLONIES IN STRAINS RECENTLY ISOLATED FROM SOURCES OTHER THAN SPUTUM Smithburn, Kenneth C. J Exp Med Article 1. Smooth, round, shiny, non-granular, and non-spreading colonies have been observed in cultures of virulent tubercle bacilli freshly isolated from eight human sources other than sputum. The classification of six of these strains as of human type was established by inoculation into rabbits and guinea pigs. 2. The 3 per cent NaOH or 6 per cent H(2)SO(4) frequently used in the isolation of tubercle bacilli are definitely unfavorable to the development of smooth colonies. 3. It was observed that smooth colonies are produced in greater number when the pH of the medium (Corper's egg yolk-glycerine) is adjusted to a point near to but slightly on the acid side of neutral. The Rockefeller University Press 1935-02-28 /pmc/articles/PMC2133226/ /pubmed/19870367 Text en Copyright © Copyright, 1935, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Smithburn, Kenneth C.
THE COLONY MORPHOLOGY OF TUBERCLE BACILLI : I. THE PRESENCE OF SMOOTH COLONIES IN STRAINS RECENTLY ISOLATED FROM SOURCES OTHER THAN SPUTUM
title THE COLONY MORPHOLOGY OF TUBERCLE BACILLI : I. THE PRESENCE OF SMOOTH COLONIES IN STRAINS RECENTLY ISOLATED FROM SOURCES OTHER THAN SPUTUM
title_full THE COLONY MORPHOLOGY OF TUBERCLE BACILLI : I. THE PRESENCE OF SMOOTH COLONIES IN STRAINS RECENTLY ISOLATED FROM SOURCES OTHER THAN SPUTUM
title_fullStr THE COLONY MORPHOLOGY OF TUBERCLE BACILLI : I. THE PRESENCE OF SMOOTH COLONIES IN STRAINS RECENTLY ISOLATED FROM SOURCES OTHER THAN SPUTUM
title_full_unstemmed THE COLONY MORPHOLOGY OF TUBERCLE BACILLI : I. THE PRESENCE OF SMOOTH COLONIES IN STRAINS RECENTLY ISOLATED FROM SOURCES OTHER THAN SPUTUM
title_short THE COLONY MORPHOLOGY OF TUBERCLE BACILLI : I. THE PRESENCE OF SMOOTH COLONIES IN STRAINS RECENTLY ISOLATED FROM SOURCES OTHER THAN SPUTUM
title_sort colony morphology of tubercle bacilli : i. the presence of smooth colonies in strains recently isolated from sources other than sputum
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133226/
https://www.ncbi.nlm.nih.gov/pubmed/19870367
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