THE PROTECTIVE ACTION OF TYPE I ANTIPNEUMOCOCCUS SERUM IN MICE : I. THE QUANTITATIVE ASPECTS OF THE MOUSE PROTECTION TEST

The mouse protection test for the evaluation of type specific antipneumococcus serum has been studied with reference to the quantitative relationships between the amount of antibody and the number of injected bacteria. By varying both these factors through wide limits certain definite characteristic...

Descripción completa

Detalles Bibliográficos
Autores principales: Goodner, Kenneth, Horsfall, Frank L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1935
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133282/
https://www.ncbi.nlm.nih.gov/pubmed/19870421
_version_ 1782142635434049536
author Goodner, Kenneth
Horsfall, Frank L.
author_facet Goodner, Kenneth
Horsfall, Frank L.
author_sort Goodner, Kenneth
collection PubMed
description The mouse protection test for the evaluation of type specific antipneumococcus serum has been studied with reference to the quantitative relationships between the amount of antibody and the number of injected bacteria. By varying both these factors through wide limits certain definite characteristics of the protection test have been defined. These are the Schwellenwert, the prozone, and the limiting titer zone. The modifications produced in the manifestations of these characteristics by changes in the technic of performing the test and also by certain non-specific reagents are described. The dependence of the outcome of the test upon variable factors intrinsic to the host is discussed.
format Text
id pubmed-2133282
institution National Center for Biotechnology Information
language English
publishDate 1935
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21332822008-04-18 THE PROTECTIVE ACTION OF TYPE I ANTIPNEUMOCOCCUS SERUM IN MICE : I. THE QUANTITATIVE ASPECTS OF THE MOUSE PROTECTION TEST Goodner, Kenneth Horsfall, Frank L. J Exp Med Article The mouse protection test for the evaluation of type specific antipneumococcus serum has been studied with reference to the quantitative relationships between the amount of antibody and the number of injected bacteria. By varying both these factors through wide limits certain definite characteristics of the protection test have been defined. These are the Schwellenwert, the prozone, and the limiting titer zone. The modifications produced in the manifestations of these characteristics by changes in the technic of performing the test and also by certain non-specific reagents are described. The dependence of the outcome of the test upon variable factors intrinsic to the host is discussed. The Rockefeller University Press 1935-08-31 /pmc/articles/PMC2133282/ /pubmed/19870421 Text en Copyright © Copyright, 1935, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Goodner, Kenneth
Horsfall, Frank L.
THE PROTECTIVE ACTION OF TYPE I ANTIPNEUMOCOCCUS SERUM IN MICE : I. THE QUANTITATIVE ASPECTS OF THE MOUSE PROTECTION TEST
title THE PROTECTIVE ACTION OF TYPE I ANTIPNEUMOCOCCUS SERUM IN MICE : I. THE QUANTITATIVE ASPECTS OF THE MOUSE PROTECTION TEST
title_full THE PROTECTIVE ACTION OF TYPE I ANTIPNEUMOCOCCUS SERUM IN MICE : I. THE QUANTITATIVE ASPECTS OF THE MOUSE PROTECTION TEST
title_fullStr THE PROTECTIVE ACTION OF TYPE I ANTIPNEUMOCOCCUS SERUM IN MICE : I. THE QUANTITATIVE ASPECTS OF THE MOUSE PROTECTION TEST
title_full_unstemmed THE PROTECTIVE ACTION OF TYPE I ANTIPNEUMOCOCCUS SERUM IN MICE : I. THE QUANTITATIVE ASPECTS OF THE MOUSE PROTECTION TEST
title_short THE PROTECTIVE ACTION OF TYPE I ANTIPNEUMOCOCCUS SERUM IN MICE : I. THE QUANTITATIVE ASPECTS OF THE MOUSE PROTECTION TEST
title_sort protective action of type i antipneumococcus serum in mice : i. the quantitative aspects of the mouse protection test
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133282/
https://www.ncbi.nlm.nih.gov/pubmed/19870421
work_keys_str_mv AT goodnerkenneth theprotectiveactionoftypeiantipneumococcusseruminmiceithequantitativeaspectsofthemouseprotectiontest
AT horsfallfrankl theprotectiveactionoftypeiantipneumococcusseruminmiceithequantitativeaspectsofthemouseprotectiontest
AT goodnerkenneth protectiveactionoftypeiantipneumococcusseruminmiceithequantitativeaspectsofthemouseprotectiontest
AT horsfallfrankl protectiveactionoftypeiantipneumococcusseruminmiceithequantitativeaspectsofthemouseprotectiontest

Ejemplares similares