THE PROTECTIVE ACTION OF TYPE I ANTIPNEUMOCOCCUS SERUM IN MICE : III. THE SIGNIFICANCE OF CERTAIN HOST FACTORS

The power of specific antipneumococcus serum to protect mice against infection with Type I Pneumococcus has been studied with reference to the capacity of the animal to utilize the specific antibodies. With a single strain of mice it was found that smaller animals and those with large numbers of whi...

Descripción completa

Detalles Bibliográficos
Autores principales: Goodner, Kenneth, Miller, D. K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1935
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133287/
https://www.ncbi.nlm.nih.gov/pubmed/19870423
_version_ 1782142636606357504
author Goodner, Kenneth
Miller, D. K.
author_facet Goodner, Kenneth
Miller, D. K.
author_sort Goodner, Kenneth
collection PubMed
description The power of specific antipneumococcus serum to protect mice against infection with Type I Pneumococcus has been studied with reference to the capacity of the animal to utilize the specific antibodies. With a single strain of mice it was found that smaller animals and those with large numbers of white cells in the peritoneal cavity are much better able to utilize the passively conferred immune principles. These two intrinsic factors were resolved into a single element; namely, the number of monocytes in the peritoneal cavity at the time of injection of culture and serum. The interrelation of the extrinsic and intrinsic factors participating in the process of protection have been discussed.
format Text
id pubmed-2133287
institution National Center for Biotechnology Information
language English
publishDate 1935
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21332872008-04-18 THE PROTECTIVE ACTION OF TYPE I ANTIPNEUMOCOCCUS SERUM IN MICE : III. THE SIGNIFICANCE OF CERTAIN HOST FACTORS Goodner, Kenneth Miller, D. K. J Exp Med Article The power of specific antipneumococcus serum to protect mice against infection with Type I Pneumococcus has been studied with reference to the capacity of the animal to utilize the specific antibodies. With a single strain of mice it was found that smaller animals and those with large numbers of white cells in the peritoneal cavity are much better able to utilize the passively conferred immune principles. These two intrinsic factors were resolved into a single element; namely, the number of monocytes in the peritoneal cavity at the time of injection of culture and serum. The interrelation of the extrinsic and intrinsic factors participating in the process of protection have been discussed. The Rockefeller University Press 1935-08-31 /pmc/articles/PMC2133287/ /pubmed/19870423 Text en Copyright © Copyright, 1935, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Goodner, Kenneth
Miller, D. K.
THE PROTECTIVE ACTION OF TYPE I ANTIPNEUMOCOCCUS SERUM IN MICE : III. THE SIGNIFICANCE OF CERTAIN HOST FACTORS
title THE PROTECTIVE ACTION OF TYPE I ANTIPNEUMOCOCCUS SERUM IN MICE : III. THE SIGNIFICANCE OF CERTAIN HOST FACTORS
title_full THE PROTECTIVE ACTION OF TYPE I ANTIPNEUMOCOCCUS SERUM IN MICE : III. THE SIGNIFICANCE OF CERTAIN HOST FACTORS
title_fullStr THE PROTECTIVE ACTION OF TYPE I ANTIPNEUMOCOCCUS SERUM IN MICE : III. THE SIGNIFICANCE OF CERTAIN HOST FACTORS
title_full_unstemmed THE PROTECTIVE ACTION OF TYPE I ANTIPNEUMOCOCCUS SERUM IN MICE : III. THE SIGNIFICANCE OF CERTAIN HOST FACTORS
title_short THE PROTECTIVE ACTION OF TYPE I ANTIPNEUMOCOCCUS SERUM IN MICE : III. THE SIGNIFICANCE OF CERTAIN HOST FACTORS
title_sort protective action of type i antipneumococcus serum in mice : iii. the significance of certain host factors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133287/
https://www.ncbi.nlm.nih.gov/pubmed/19870423
work_keys_str_mv AT goodnerkenneth theprotectiveactionoftypeiantipneumococcusseruminmiceiiithesignificanceofcertainhostfactors
AT millerdk theprotectiveactionoftypeiantipneumococcusseruminmiceiiithesignificanceofcertainhostfactors
AT goodnerkenneth protectiveactionoftypeiantipneumococcusseruminmiceiiithesignificanceofcertainhostfactors
AT millerdk protectiveactionoftypeiantipneumococcusseruminmiceiiithesignificanceofcertainhostfactors

Ejemplares similares