CELLULAR REACTIONS TO WAX-LIKE MATERIALS FROM ACID-FAST BACTERIA : THE UNSAPONIFIABLE FRACTION FROM THE TUBERCLE BACILLUS, STRAIN H-37

1. The unsaponifiable fractions of the Mycobacteria, though insoluble in water and extremely stable chemical compounds, are nevertheless remarkable stimulants of cells. 2. They give rise to new monocytes which surround these waxes and then fuse into giant cells which engulf them. 3. The property of...

Descripción completa

Detalles Bibliográficos
Autores principales: Sabin, F. R., Smithburn, K. C., Thomas, R. M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1935
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133308/
https://www.ncbi.nlm.nih.gov/pubmed/19870446
_version_ 1782142641601773568
author Sabin, F. R.
Smithburn, K. C.
Thomas, R. M.
author_facet Sabin, F. R.
Smithburn, K. C.
Thomas, R. M.
author_sort Sabin, F. R.
collection PubMed
description 1. The unsaponifiable fractions of the Mycobacteria, though insoluble in water and extremely stable chemical compounds, are nevertheless remarkable stimulants of cells. 2. They give rise to new monocytes which surround these waxes and then fuse into giant cells which engulf them. 3. The property of acid-fastness of the waxes makes it possible to identify them within the giant cells which have phagocytized them. 4. Within the foreign body giant cells the waxes are slowly disintegrated. They appear not to damage the cells which engulf them, and hence one may infer that they take no part in caseation. 5. They have no effect on the resistance of the host.
format Text
id pubmed-2133308
institution National Center for Biotechnology Information
language English
publishDate 1935
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21333082008-04-18 CELLULAR REACTIONS TO WAX-LIKE MATERIALS FROM ACID-FAST BACTERIA : THE UNSAPONIFIABLE FRACTION FROM THE TUBERCLE BACILLUS, STRAIN H-37 Sabin, F. R. Smithburn, K. C. Thomas, R. M. J Exp Med Article 1. The unsaponifiable fractions of the Mycobacteria, though insoluble in water and extremely stable chemical compounds, are nevertheless remarkable stimulants of cells. 2. They give rise to new monocytes which surround these waxes and then fuse into giant cells which engulf them. 3. The property of acid-fastness of the waxes makes it possible to identify them within the giant cells which have phagocytized them. 4. Within the foreign body giant cells the waxes are slowly disintegrated. They appear not to damage the cells which engulf them, and hence one may infer that they take no part in caseation. 5. They have no effect on the resistance of the host. The Rockefeller University Press 1935-11-30 /pmc/articles/PMC2133308/ /pubmed/19870446 Text en Copyright © Copyright, 1935, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Sabin, F. R.
Smithburn, K. C.
Thomas, R. M.
CELLULAR REACTIONS TO WAX-LIKE MATERIALS FROM ACID-FAST BACTERIA : THE UNSAPONIFIABLE FRACTION FROM THE TUBERCLE BACILLUS, STRAIN H-37
title CELLULAR REACTIONS TO WAX-LIKE MATERIALS FROM ACID-FAST BACTERIA : THE UNSAPONIFIABLE FRACTION FROM THE TUBERCLE BACILLUS, STRAIN H-37
title_full CELLULAR REACTIONS TO WAX-LIKE MATERIALS FROM ACID-FAST BACTERIA : THE UNSAPONIFIABLE FRACTION FROM THE TUBERCLE BACILLUS, STRAIN H-37
title_fullStr CELLULAR REACTIONS TO WAX-LIKE MATERIALS FROM ACID-FAST BACTERIA : THE UNSAPONIFIABLE FRACTION FROM THE TUBERCLE BACILLUS, STRAIN H-37
title_full_unstemmed CELLULAR REACTIONS TO WAX-LIKE MATERIALS FROM ACID-FAST BACTERIA : THE UNSAPONIFIABLE FRACTION FROM THE TUBERCLE BACILLUS, STRAIN H-37
title_short CELLULAR REACTIONS TO WAX-LIKE MATERIALS FROM ACID-FAST BACTERIA : THE UNSAPONIFIABLE FRACTION FROM THE TUBERCLE BACILLUS, STRAIN H-37
title_sort cellular reactions to wax-like materials from acid-fast bacteria : the unsaponifiable fraction from the tubercle bacillus, strain h-37
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133308/
https://www.ncbi.nlm.nih.gov/pubmed/19870446
work_keys_str_mv AT sabinfr cellularreactionstowaxlikematerialsfromacidfastbacteriatheunsaponifiablefractionfromthetuberclebacillusstrainh37
AT smithburnkc cellularreactionstowaxlikematerialsfromacidfastbacteriatheunsaponifiablefractionfromthetuberclebacillusstrainh37
AT thomasrm cellularreactionstowaxlikematerialsfromacidfastbacteriatheunsaponifiablefractionfromthetuberclebacillusstrainh37

Ejemplares similares