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ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS

The phenomena observed on absorption of immune sera to azoproteins with heterologous azoantigens lead to the conclusion that in general the sera do not contain a single antibody but antibody fractions somewhat different in their reactivity for heterologous antigens. From the constitution of the azoc...

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Detalles Bibliográficos
Autores principales: Landsteiner, K., van der Scheer, J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1936
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133341/
https://www.ncbi.nlm.nih.gov/pubmed/19870475
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author Landsteiner, K.
van der Scheer, J.
author_facet Landsteiner, K.
van der Scheer, J.
author_sort Landsteiner, K.
collection PubMed
description The phenomena observed on absorption of immune sera to azoproteins with heterologous azoantigens lead to the conclusion that in general the sera do not contain a single antibody but antibody fractions somewhat different in their reactivity for heterologous antigens. From the constitution of the azocomponent it follows that these fractions cannot be specific for distinct chemical groups in the molecule. In fact, inhibition experiments showed that in the cases examined the various antibodies are all specifically directed towards the whole molecule of the homologous hapten.
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spelling pubmed-21333412008-04-18 ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS Landsteiner, K. van der Scheer, J. J Exp Med Article The phenomena observed on absorption of immune sera to azoproteins with heterologous azoantigens lead to the conclusion that in general the sera do not contain a single antibody but antibody fractions somewhat different in their reactivity for heterologous antigens. From the constitution of the azocomponent it follows that these fractions cannot be specific for distinct chemical groups in the molecule. In fact, inhibition experiments showed that in the cases examined the various antibodies are all specifically directed towards the whole molecule of the homologous hapten. The Rockefeller University Press 1936-02-29 /pmc/articles/PMC2133341/ /pubmed/19870475 Text en Copyright © Copyright, 1936, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Landsteiner, K.
van der Scheer, J.
ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS
title ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS
title_full ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS
title_fullStr ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS
title_full_unstemmed ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS
title_short ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS
title_sort on cross reactions of immune sera to azoproteins
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133341/
https://www.ncbi.nlm.nih.gov/pubmed/19870475
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