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ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS
The phenomena observed on absorption of immune sera to azoproteins with heterologous azoantigens lead to the conclusion that in general the sera do not contain a single antibody but antibody fractions somewhat different in their reactivity for heterologous antigens. From the constitution of the azoc...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1936
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133341/ https://www.ncbi.nlm.nih.gov/pubmed/19870475 |
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author | Landsteiner, K. van der Scheer, J. |
author_facet | Landsteiner, K. van der Scheer, J. |
author_sort | Landsteiner, K. |
collection | PubMed |
description | The phenomena observed on absorption of immune sera to azoproteins with heterologous azoantigens lead to the conclusion that in general the sera do not contain a single antibody but antibody fractions somewhat different in their reactivity for heterologous antigens. From the constitution of the azocomponent it follows that these fractions cannot be specific for distinct chemical groups in the molecule. In fact, inhibition experiments showed that in the cases examined the various antibodies are all specifically directed towards the whole molecule of the homologous hapten. |
format | Text |
id | pubmed-2133341 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1936 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21333412008-04-18 ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS Landsteiner, K. van der Scheer, J. J Exp Med Article The phenomena observed on absorption of immune sera to azoproteins with heterologous azoantigens lead to the conclusion that in general the sera do not contain a single antibody but antibody fractions somewhat different in their reactivity for heterologous antigens. From the constitution of the azocomponent it follows that these fractions cannot be specific for distinct chemical groups in the molecule. In fact, inhibition experiments showed that in the cases examined the various antibodies are all specifically directed towards the whole molecule of the homologous hapten. The Rockefeller University Press 1936-02-29 /pmc/articles/PMC2133341/ /pubmed/19870475 Text en Copyright © Copyright, 1936, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Landsteiner, K. van der Scheer, J. ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS |
title | ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS |
title_full | ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS |
title_fullStr | ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS |
title_full_unstemmed | ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS |
title_short | ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS |
title_sort | on cross reactions of immune sera to azoproteins |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133341/ https://www.ncbi.nlm.nih.gov/pubmed/19870475 |
work_keys_str_mv | AT landsteinerk oncrossreactionsofimmuneseratoazoproteins AT vanderscheerj oncrossreactionsofimmuneseratoazoproteins |