STUDIES IN SYNERGY : THE SYNERGIC ACTION OF STAPHYLOTOXIN AND BEEF LENS EXTRACT IN RABBITS

The degree of immunization and sensitization of rabbits following injections of beef lens is markedly increased when the animals are under the influence of staphylotoxin. Since the effect of the latter is exerted when the two substances are introduced separately into the same tissues with several ho...

Descripción completa

Detalles Bibliográficos
Autores principales: Swift, Homer F., Schultz, Mark P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1936
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133363/
https://www.ncbi.nlm.nih.gov/pubmed/19870498
_version_ 1782142653685563392
author Swift, Homer F.
Schultz, Mark P.
author_facet Swift, Homer F.
Schultz, Mark P.
author_sort Swift, Homer F.
collection PubMed
description The degree of immunization and sensitization of rabbits following injections of beef lens is markedly increased when the animals are under the influence of staphylotoxin. Since the effect of the latter is exerted when the two substances are introduced separately into the same tissues with several hours elapsing between injections, or into different veins, it appears that an intimate association of them is unnecessary. A stimulating action of the toxin on the antibody-forming cells is a more probable explanation of the phenomena observed. Animals actively immune to staphylotoxin fail to show any synergic effect of this toxin when introduced with beef lens. Neutralization of the toxin in vitro, on the other hand, fails to eliminate this stimulating effect.
format Text
id pubmed-2133363
institution National Center for Biotechnology Information
language English
publishDate 1936
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21333632008-04-18 STUDIES IN SYNERGY : THE SYNERGIC ACTION OF STAPHYLOTOXIN AND BEEF LENS EXTRACT IN RABBITS Swift, Homer F. Schultz, Mark P. J Exp Med Article The degree of immunization and sensitization of rabbits following injections of beef lens is markedly increased when the animals are under the influence of staphylotoxin. Since the effect of the latter is exerted when the two substances are introduced separately into the same tissues with several hours elapsing between injections, or into different veins, it appears that an intimate association of them is unnecessary. A stimulating action of the toxin on the antibody-forming cells is a more probable explanation of the phenomena observed. Animals actively immune to staphylotoxin fail to show any synergic effect of this toxin when introduced with beef lens. Neutralization of the toxin in vitro, on the other hand, fails to eliminate this stimulating effect. The Rockefeller University Press 1936-04-30 /pmc/articles/PMC2133363/ /pubmed/19870498 Text en Copyright © Copyright, 1936, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Swift, Homer F.
Schultz, Mark P.
STUDIES IN SYNERGY : THE SYNERGIC ACTION OF STAPHYLOTOXIN AND BEEF LENS EXTRACT IN RABBITS
title STUDIES IN SYNERGY : THE SYNERGIC ACTION OF STAPHYLOTOXIN AND BEEF LENS EXTRACT IN RABBITS
title_full STUDIES IN SYNERGY : THE SYNERGIC ACTION OF STAPHYLOTOXIN AND BEEF LENS EXTRACT IN RABBITS
title_fullStr STUDIES IN SYNERGY : THE SYNERGIC ACTION OF STAPHYLOTOXIN AND BEEF LENS EXTRACT IN RABBITS
title_full_unstemmed STUDIES IN SYNERGY : THE SYNERGIC ACTION OF STAPHYLOTOXIN AND BEEF LENS EXTRACT IN RABBITS
title_short STUDIES IN SYNERGY : THE SYNERGIC ACTION OF STAPHYLOTOXIN AND BEEF LENS EXTRACT IN RABBITS
title_sort studies in synergy : the synergic action of staphylotoxin and beef lens extract in rabbits
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133363/
https://www.ncbi.nlm.nih.gov/pubmed/19870498
work_keys_str_mv AT swifthomerf studiesinsynergythesynergicactionofstaphylotoxinandbeeflensextractinrabbits
AT schultzmarkp studiesinsynergythesynergicactionofstaphylotoxinandbeeflensextractinrabbits

Ejemplares similares