QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : EFFECT OF SALTS ON THE REACTION

1. A quantitative study has been made of the effect on the precipitin reaction between the specific polysaccharide of Type III pneumococcus and the homologous antibody of salt concentrations ranging from O.1 M to 1.79 M, including the effect of ions of higher valence. 2. Within these limits, observe...

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Detalles Bibliográficos
Autores principales: Heidelberger, Michael, Kendall, Forrest E., Teorell, Torsten
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1936
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133402/
https://www.ncbi.nlm.nih.gov/pubmed/19870507
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author Heidelberger, Michael
Kendall, Forrest E.
Teorell, Torsten
author_facet Heidelberger, Michael
Kendall, Forrest E.
Teorell, Torsten
author_sort Heidelberger, Michael
collection PubMed
description 1. A quantitative study has been made of the effect on the precipitin reaction between the specific polysaccharide of Type III pneumococcus and the homologous antibody of salt concentrations ranging from O.1 M to 1.79 M, including the effect of ions of higher valence. 2. Within these limits, observed decreases in precipitated antibody with increasing salt concentration appear to be due to a decrease in the amount of antibody combined with the S III, rather than to an increase in solubility of the S III-antibody compounds. 3. The egg albumin-antibody reaction is far less sensitive to changes in salt concentration than is the S III-antibody reaction.
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spelling pubmed-21334022008-04-18 QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : EFFECT OF SALTS ON THE REACTION Heidelberger, Michael Kendall, Forrest E. Teorell, Torsten J Exp Med Article 1. A quantitative study has been made of the effect on the precipitin reaction between the specific polysaccharide of Type III pneumococcus and the homologous antibody of salt concentrations ranging from O.1 M to 1.79 M, including the effect of ions of higher valence. 2. Within these limits, observed decreases in precipitated antibody with increasing salt concentration appear to be due to a decrease in the amount of antibody combined with the S III, rather than to an increase in solubility of the S III-antibody compounds. 3. The egg albumin-antibody reaction is far less sensitive to changes in salt concentration than is the S III-antibody reaction. The Rockefeller University Press 1936-05-31 /pmc/articles/PMC2133402/ /pubmed/19870507 Text en Copyright © Copyright, 1936, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Heidelberger, Michael
Kendall, Forrest E.
Teorell, Torsten
QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : EFFECT OF SALTS ON THE REACTION
title QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : EFFECT OF SALTS ON THE REACTION
title_full QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : EFFECT OF SALTS ON THE REACTION
title_fullStr QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : EFFECT OF SALTS ON THE REACTION
title_full_unstemmed QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : EFFECT OF SALTS ON THE REACTION
title_short QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : EFFECT OF SALTS ON THE REACTION
title_sort quantitative studies on the precipitin reaction : effect of salts on the reaction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133402/
https://www.ncbi.nlm.nih.gov/pubmed/19870507
work_keys_str_mv AT heidelbergermichael quantitativestudiesontheprecipitinreactioneffectofsaltsonthereaction
AT kendallforreste quantitativestudiesontheprecipitinreactioneffectofsaltsonthereaction
AT teorelltorsten quantitativestudiesontheprecipitinreactioneffectofsaltsonthereaction

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