THE STANDARDIZATION OF LONGEVITY AGAINST DOSE IN EXPERIMENTAL TUBERCULOSIS BY INTRACEREBRAL INOCULATION

Intracerebral inoculation of tuberde bacilli into normal guinea pigs induces acute meningoencephalitis with minor metastatic lesions. The disease is fatal in a relatively short time and is characterized by a rather typical succession of symptoms and a fairly characteristic temperature curve. The dis...

Descripción completa

Detalles Bibliográficos
Autor principal: Smithburn, Kenneth C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1936
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133452/
https://www.ncbi.nlm.nih.gov/pubmed/19870568
_version_ 1782142672674226176
author Smithburn, Kenneth C.
author_facet Smithburn, Kenneth C.
author_sort Smithburn, Kenneth C.
collection PubMed
description Intracerebral inoculation of tuberde bacilli into normal guinea pigs induces acute meningoencephalitis with minor metastatic lesions. The disease is fatal in a relatively short time and is characterized by a rather typical succession of symptoms and a fairly characteristic temperature curve. The disease is produced by very small numbers of bacilli; and under standard conditions, survival time is so uniform as to make possible quantitative or titration experiments. Certain possible applications of the method are discussed.
format Text
id pubmed-2133452
institution National Center for Biotechnology Information
language English
publishDate 1936
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21334522008-04-18 THE STANDARDIZATION OF LONGEVITY AGAINST DOSE IN EXPERIMENTAL TUBERCULOSIS BY INTRACEREBRAL INOCULATION Smithburn, Kenneth C. J Exp Med Article Intracerebral inoculation of tuberde bacilli into normal guinea pigs induces acute meningoencephalitis with minor metastatic lesions. The disease is fatal in a relatively short time and is characterized by a rather typical succession of symptoms and a fairly characteristic temperature curve. The disease is produced by very small numbers of bacilli; and under standard conditions, survival time is so uniform as to make possible quantitative or titration experiments. Certain possible applications of the method are discussed. The Rockefeller University Press 1936-10-31 /pmc/articles/PMC2133452/ /pubmed/19870568 Text en Copyright © Copyright, 1936, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Smithburn, Kenneth C.
THE STANDARDIZATION OF LONGEVITY AGAINST DOSE IN EXPERIMENTAL TUBERCULOSIS BY INTRACEREBRAL INOCULATION
title THE STANDARDIZATION OF LONGEVITY AGAINST DOSE IN EXPERIMENTAL TUBERCULOSIS BY INTRACEREBRAL INOCULATION
title_full THE STANDARDIZATION OF LONGEVITY AGAINST DOSE IN EXPERIMENTAL TUBERCULOSIS BY INTRACEREBRAL INOCULATION
title_fullStr THE STANDARDIZATION OF LONGEVITY AGAINST DOSE IN EXPERIMENTAL TUBERCULOSIS BY INTRACEREBRAL INOCULATION
title_full_unstemmed THE STANDARDIZATION OF LONGEVITY AGAINST DOSE IN EXPERIMENTAL TUBERCULOSIS BY INTRACEREBRAL INOCULATION
title_short THE STANDARDIZATION OF LONGEVITY AGAINST DOSE IN EXPERIMENTAL TUBERCULOSIS BY INTRACEREBRAL INOCULATION
title_sort standardization of longevity against dose in experimental tuberculosis by intracerebral inoculation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133452/
https://www.ncbi.nlm.nih.gov/pubmed/19870568
work_keys_str_mv AT smithburnkennethc thestandardizationoflongevityagainstdoseinexperimentaltuberculosisbyintracerebralinoculation
AT smithburnkennethc standardizationoflongevityagainstdoseinexperimentaltuberculosisbyintracerebralinoculation

Ejemplares similares