EXPERIMENTAL NEPHRITIS IN RATS INDUCED BY INJECTION OF ANTI-KIDNEY SERUM : IV. PREVENTION OF THE INJURIOUS EFFECTS OF NEPHROTOXIN IN VIVO BY KIDNEY EXTRACT

A saline extract of perfused rat kidney administered intravenously to rats immediately before injecting an anti-rat-kidney serum, by the same route, prevents renal damage. A preliminary injection of physiological salt solution or of an extract of perfused rat liver has no preventive effect. These fi...

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Detalles Bibliográficos
Autores principales: Swift, Homer F., Smadel, Joseph E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1937
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133501/
https://www.ncbi.nlm.nih.gov/pubmed/19870618
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author Swift, Homer F.
Smadel, Joseph E.
author_facet Swift, Homer F.
Smadel, Joseph E.
author_sort Swift, Homer F.
collection PubMed
description A saline extract of perfused rat kidney administered intravenously to rats immediately before injecting an anti-rat-kidney serum, by the same route, prevents renal damage. A preliminary injection of physiological salt solution or of an extract of perfused rat liver has no preventive effect. These findings are a further indication that the nephrotoxic effect induced by anti-kidney serum is dependent upon a relatively organ specific antibody, nephrotoxin.
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spelling pubmed-21335012008-04-18 EXPERIMENTAL NEPHRITIS IN RATS INDUCED BY INJECTION OF ANTI-KIDNEY SERUM : IV. PREVENTION OF THE INJURIOUS EFFECTS OF NEPHROTOXIN IN VIVO BY KIDNEY EXTRACT Swift, Homer F. Smadel, Joseph E. J Exp Med Article A saline extract of perfused rat kidney administered intravenously to rats immediately before injecting an anti-rat-kidney serum, by the same route, prevents renal damage. A preliminary injection of physiological salt solution or of an extract of perfused rat liver has no preventive effect. These findings are a further indication that the nephrotoxic effect induced by anti-kidney serum is dependent upon a relatively organ specific antibody, nephrotoxin. The Rockefeller University Press 1937-03-31 /pmc/articles/PMC2133501/ /pubmed/19870618 Text en Copyright © Copyright, 1937, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Swift, Homer F.
Smadel, Joseph E.
EXPERIMENTAL NEPHRITIS IN RATS INDUCED BY INJECTION OF ANTI-KIDNEY SERUM : IV. PREVENTION OF THE INJURIOUS EFFECTS OF NEPHROTOXIN IN VIVO BY KIDNEY EXTRACT
title EXPERIMENTAL NEPHRITIS IN RATS INDUCED BY INJECTION OF ANTI-KIDNEY SERUM : IV. PREVENTION OF THE INJURIOUS EFFECTS OF NEPHROTOXIN IN VIVO BY KIDNEY EXTRACT
title_full EXPERIMENTAL NEPHRITIS IN RATS INDUCED BY INJECTION OF ANTI-KIDNEY SERUM : IV. PREVENTION OF THE INJURIOUS EFFECTS OF NEPHROTOXIN IN VIVO BY KIDNEY EXTRACT
title_fullStr EXPERIMENTAL NEPHRITIS IN RATS INDUCED BY INJECTION OF ANTI-KIDNEY SERUM : IV. PREVENTION OF THE INJURIOUS EFFECTS OF NEPHROTOXIN IN VIVO BY KIDNEY EXTRACT
title_full_unstemmed EXPERIMENTAL NEPHRITIS IN RATS INDUCED BY INJECTION OF ANTI-KIDNEY SERUM : IV. PREVENTION OF THE INJURIOUS EFFECTS OF NEPHROTOXIN IN VIVO BY KIDNEY EXTRACT
title_short EXPERIMENTAL NEPHRITIS IN RATS INDUCED BY INJECTION OF ANTI-KIDNEY SERUM : IV. PREVENTION OF THE INJURIOUS EFFECTS OF NEPHROTOXIN IN VIVO BY KIDNEY EXTRACT
title_sort experimental nephritis in rats induced by injection of anti-kidney serum : iv. prevention of the injurious effects of nephrotoxin in vivo by kidney extract
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133501/
https://www.ncbi.nlm.nih.gov/pubmed/19870618
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AT smadeljosephe experimentalnephritisinratsinducedbyinjectionofantikidneyserumivpreventionoftheinjuriouseffectsofnephrotoxininvivobykidneyextract

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