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CHEMICAL INVESTIGATIONS ON THE ACTIVE PRINCIPLES OF THE PHENOMENON OF LOCAL SKIN REACTIVITY TO BACTERIAL FILTRATES : III. APPLICATION OF DIALYSIS TO THE PRODUCTION OF THE ACTIVE PRINCIPLES IN FLUID MEDIA
B. coli, meningococcus, and B. typhosus have been cultivated in a diffused broth medium, prepared by immersing cellophane bags containing saline into nutrient broth. An abundant growth occurred inside the bags, while the outside broth remained sterile. Under these conditions, the production of the a...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1938
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133546/ https://www.ncbi.nlm.nih.gov/pubmed/19870703 |
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author | Morell, S. A. Shwartzman, Gregory |
author_facet | Morell, S. A. Shwartzman, Gregory |
author_sort | Morell, S. A. |
collection | PubMed |
description | B. coli, meningococcus, and B. typhosus have been cultivated in a diffused broth medium, prepared by immersing cellophane bags containing saline into nutrient broth. An abundant growth occurred inside the bags, while the outside broth remained sterile. Under these conditions, the production of the active principles of the phenomenon of local skin reactivity to bacterial filtrates has been consistent. When the culture filtrates so obtained were redialyzed against saline, active preparations were obtained which were practically free from non-specific ingredients. |
format | Text |
id | pubmed-2133546 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1938 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21335462008-04-18 CHEMICAL INVESTIGATIONS ON THE ACTIVE PRINCIPLES OF THE PHENOMENON OF LOCAL SKIN REACTIVITY TO BACTERIAL FILTRATES : III. APPLICATION OF DIALYSIS TO THE PRODUCTION OF THE ACTIVE PRINCIPLES IN FLUID MEDIA Morell, S. A. Shwartzman, Gregory J Exp Med Article B. coli, meningococcus, and B. typhosus have been cultivated in a diffused broth medium, prepared by immersing cellophane bags containing saline into nutrient broth. An abundant growth occurred inside the bags, while the outside broth remained sterile. Under these conditions, the production of the active principles of the phenomenon of local skin reactivity to bacterial filtrates has been consistent. When the culture filtrates so obtained were redialyzed against saline, active preparations were obtained which were practically free from non-specific ingredients. The Rockefeller University Press 1938-01-01 /pmc/articles/PMC2133546/ /pubmed/19870703 Text en Copyright © Copyright, 1938, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Morell, S. A. Shwartzman, Gregory CHEMICAL INVESTIGATIONS ON THE ACTIVE PRINCIPLES OF THE PHENOMENON OF LOCAL SKIN REACTIVITY TO BACTERIAL FILTRATES : III. APPLICATION OF DIALYSIS TO THE PRODUCTION OF THE ACTIVE PRINCIPLES IN FLUID MEDIA |
title | CHEMICAL INVESTIGATIONS ON THE ACTIVE PRINCIPLES OF THE PHENOMENON OF LOCAL SKIN REACTIVITY TO BACTERIAL FILTRATES : III. APPLICATION OF DIALYSIS TO THE PRODUCTION OF THE ACTIVE PRINCIPLES IN FLUID MEDIA |
title_full | CHEMICAL INVESTIGATIONS ON THE ACTIVE PRINCIPLES OF THE PHENOMENON OF LOCAL SKIN REACTIVITY TO BACTERIAL FILTRATES : III. APPLICATION OF DIALYSIS TO THE PRODUCTION OF THE ACTIVE PRINCIPLES IN FLUID MEDIA |
title_fullStr | CHEMICAL INVESTIGATIONS ON THE ACTIVE PRINCIPLES OF THE PHENOMENON OF LOCAL SKIN REACTIVITY TO BACTERIAL FILTRATES : III. APPLICATION OF DIALYSIS TO THE PRODUCTION OF THE ACTIVE PRINCIPLES IN FLUID MEDIA |
title_full_unstemmed | CHEMICAL INVESTIGATIONS ON THE ACTIVE PRINCIPLES OF THE PHENOMENON OF LOCAL SKIN REACTIVITY TO BACTERIAL FILTRATES : III. APPLICATION OF DIALYSIS TO THE PRODUCTION OF THE ACTIVE PRINCIPLES IN FLUID MEDIA |
title_short | CHEMICAL INVESTIGATIONS ON THE ACTIVE PRINCIPLES OF THE PHENOMENON OF LOCAL SKIN REACTIVITY TO BACTERIAL FILTRATES : III. APPLICATION OF DIALYSIS TO THE PRODUCTION OF THE ACTIVE PRINCIPLES IN FLUID MEDIA |
title_sort | chemical investigations on the active principles of the phenomenon of local skin reactivity to bacterial filtrates : iii. application of dialysis to the production of the active principles in fluid media |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133546/ https://www.ncbi.nlm.nih.gov/pubmed/19870703 |
work_keys_str_mv | AT morellsa chemicalinvestigationsontheactiveprinciplesofthephenomenonoflocalskinreactivitytobacterialfiltratesiiiapplicationofdialysistotheproductionoftheactiveprinciplesinfluidmedia AT shwartzmangregory chemicalinvestigationsontheactiveprinciplesofthephenomenonoflocalskinreactivitytobacterialfiltratesiiiapplicationofdialysistotheproductionoftheactiveprinciplesinfluidmedia |