MECHANISM OF THE LYSIS OF PNEUMOCOCCI BY FREEZING AND THAWING, BILE, AND OTHER AGENTS

Pneumococci, living or dead, are soluble in bile when: (a) the autolytic enzymes are still present in a potentially active form; (b) conditions are favorable for enzymatic action. Bile solubility of pneumococci involves as a necessary step one, or a few, of the many stages of the autolytic complex....

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Detalles Bibliográficos
Autor principal: Dubos, René J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1937
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133589/
https://www.ncbi.nlm.nih.gov/pubmed/19870644
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author Dubos, René J.
author_facet Dubos, René J.
author_sort Dubos, René J.
collection PubMed
description Pneumococci, living or dead, are soluble in bile when: (a) the autolytic enzymes are still present in a potentially active form; (b) conditions are favorable for enzymatic action. Bile solubility of pneumococci involves as a necessary step one, or a few, of the many stages of the autolytic complex. These observations hold true for the disruption of pneumococci by freezing and thawing, by previous desiccation with cold acetone, and by dilute solutions of antiseptics. A possible mechanism is discussed to account for these forms of lysis.
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spelling pubmed-21335892008-04-18 MECHANISM OF THE LYSIS OF PNEUMOCOCCI BY FREEZING AND THAWING, BILE, AND OTHER AGENTS Dubos, René J. J Exp Med Article Pneumococci, living or dead, are soluble in bile when: (a) the autolytic enzymes are still present in a potentially active form; (b) conditions are favorable for enzymatic action. Bile solubility of pneumococci involves as a necessary step one, or a few, of the many stages of the autolytic complex. These observations hold true for the disruption of pneumococci by freezing and thawing, by previous desiccation with cold acetone, and by dilute solutions of antiseptics. A possible mechanism is discussed to account for these forms of lysis. The Rockefeller University Press 1937-06-30 /pmc/articles/PMC2133589/ /pubmed/19870644 Text en Copyright © Copyright, 1937, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Dubos, René J.
MECHANISM OF THE LYSIS OF PNEUMOCOCCI BY FREEZING AND THAWING, BILE, AND OTHER AGENTS
title MECHANISM OF THE LYSIS OF PNEUMOCOCCI BY FREEZING AND THAWING, BILE, AND OTHER AGENTS
title_full MECHANISM OF THE LYSIS OF PNEUMOCOCCI BY FREEZING AND THAWING, BILE, AND OTHER AGENTS
title_fullStr MECHANISM OF THE LYSIS OF PNEUMOCOCCI BY FREEZING AND THAWING, BILE, AND OTHER AGENTS
title_full_unstemmed MECHANISM OF THE LYSIS OF PNEUMOCOCCI BY FREEZING AND THAWING, BILE, AND OTHER AGENTS
title_short MECHANISM OF THE LYSIS OF PNEUMOCOCCI BY FREEZING AND THAWING, BILE, AND OTHER AGENTS
title_sort mechanism of the lysis of pneumococci by freezing and thawing, bile, and other agents
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133589/
https://www.ncbi.nlm.nih.gov/pubmed/19870644
work_keys_str_mv AT dubosrenej mechanismofthelysisofpneumococcibyfreezingandthawingbileandotheragents

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