DOES LIVER SUPPLY FACTORS IN ADDITION TO IRON AND COPPER FOR HEMOGLOBIN REGENERATION IN NUTRITIONAL ANEMIA?

1. Our data indicate that the effectiveness of whole liver in the treatment of nutritional anemia in rats induced by a milk diet is directly proportional to its available iron and copper content. The other constituents in liver are not needed for maximum hemoglobin regeneration on a diet of milk, ir...

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Detalles Bibliográficos
Autores principales: Hart, E. B., Elvehjem, C. A., Kohler, G. O.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1937
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133601/
https://www.ncbi.nlm.nih.gov/pubmed/19870652
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author Hart, E. B.
Elvehjem, C. A.
Kohler, G. O.
author_facet Hart, E. B.
Elvehjem, C. A.
Kohler, G. O.
author_sort Hart, E. B.
collection PubMed
description 1. Our data indicate that the effectiveness of whole liver in the treatment of nutritional anemia in rats induced by a milk diet is directly proportional to its available iron and copper content. The other constituents in liver are not needed for maximum hemoglobin regeneration on a diet of milk, iron, copper, and manganese. 2. Commercial preparations of liver products with iron or iron and copper vary greatly in their hemoglobin-regenerating efficiency in rats with nutritional anemia. The variation is correlated directly with the iron and copper content of the preparation. When the copper-iron ratio was too wide hemoglobin regeneration was checked, although the iron supply was sufficient for optimum regeneration.
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spelling pubmed-21336012008-04-18 DOES LIVER SUPPLY FACTORS IN ADDITION TO IRON AND COPPER FOR HEMOGLOBIN REGENERATION IN NUTRITIONAL ANEMIA? Hart, E. B. Elvehjem, C. A. Kohler, G. O. J Exp Med Article 1. Our data indicate that the effectiveness of whole liver in the treatment of nutritional anemia in rats induced by a milk diet is directly proportional to its available iron and copper content. The other constituents in liver are not needed for maximum hemoglobin regeneration on a diet of milk, iron, copper, and manganese. 2. Commercial preparations of liver products with iron or iron and copper vary greatly in their hemoglobin-regenerating efficiency in rats with nutritional anemia. The variation is correlated directly with the iron and copper content of the preparation. When the copper-iron ratio was too wide hemoglobin regeneration was checked, although the iron supply was sufficient for optimum regeneration. The Rockefeller University Press 1937-07-31 /pmc/articles/PMC2133601/ /pubmed/19870652 Text en Copyright © Copyright, 1937, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Hart, E. B.
Elvehjem, C. A.
Kohler, G. O.
DOES LIVER SUPPLY FACTORS IN ADDITION TO IRON AND COPPER FOR HEMOGLOBIN REGENERATION IN NUTRITIONAL ANEMIA?
title DOES LIVER SUPPLY FACTORS IN ADDITION TO IRON AND COPPER FOR HEMOGLOBIN REGENERATION IN NUTRITIONAL ANEMIA?
title_full DOES LIVER SUPPLY FACTORS IN ADDITION TO IRON AND COPPER FOR HEMOGLOBIN REGENERATION IN NUTRITIONAL ANEMIA?
title_fullStr DOES LIVER SUPPLY FACTORS IN ADDITION TO IRON AND COPPER FOR HEMOGLOBIN REGENERATION IN NUTRITIONAL ANEMIA?
title_full_unstemmed DOES LIVER SUPPLY FACTORS IN ADDITION TO IRON AND COPPER FOR HEMOGLOBIN REGENERATION IN NUTRITIONAL ANEMIA?
title_short DOES LIVER SUPPLY FACTORS IN ADDITION TO IRON AND COPPER FOR HEMOGLOBIN REGENERATION IN NUTRITIONAL ANEMIA?
title_sort does liver supply factors in addition to iron and copper for hemoglobin regeneration in nutritional anemia?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133601/
https://www.ncbi.nlm.nih.gov/pubmed/19870652
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