THE CULTURE OF WHOLE ORGANS : III. THE PROBLEM OF ANTIHORMONES STUDIED ON ISOLATED LIVING THYROID GLANDS

1. Perfusion of isolated thyroid glands from rabbits, made refractory to the action of the thyro-stimulating factor from the hypophysis by repeated injections for 2 months, has shown that in this condition the thyroid epithelium responds to pituitary stimulation. 2. The serum from refractory rabbits...

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Detalles Bibliográficos
Autor principal: Okkels, Harald
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1937
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133617/
https://www.ncbi.nlm.nih.gov/pubmed/19870664
Descripción
Sumario:1. Perfusion of isolated thyroid glands from rabbits, made refractory to the action of the thyro-stimulating factor from the hypophysis by repeated injections for 2 months, has shown that in this condition the thyroid epithelium responds to pituitary stimulation. 2. The serum from refractory rabbits does not neutralize completely the thyro-stimulating effect of anterior pituitary extract upon an isolated normal thyroid gland. 3. It is believed that tissues other than the thyroid play a rôle in bringing about the phenomena which have been described as refractoriness against a prolonged action of the thyro-stimulating pituitary factor.

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