ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS : II. ANTIGENS WITH AZOCOMPONENTS CONTAINING TWO DETERMINANT GROUPS

Azoproteins have been prepared with azocomponents possessing two serologically active groups. On immunization with such antigens immune sera were obtained containing two separate, unrelated antibodies, each specific for one of the two groups and separable by absorption. In other cases one of the two...

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Detalles Bibliográficos
Autores principales: Landsteiner, K., van der Scheer, J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1938
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133629/
https://www.ncbi.nlm.nih.gov/pubmed/19870750
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author Landsteiner, K.
van der Scheer, J.
author_facet Landsteiner, K.
van der Scheer, J.
author_sort Landsteiner, K.
collection PubMed
description Azoproteins have been prepared with azocomponents possessing two serologically active groups. On immunization with such antigens immune sera were obtained containing two separate, unrelated antibodies, each specific for one of the two groups and separable by absorption. In other cases one of the two structures was dominant, in that antibodies were formed only towards this and not towards the other grouping. The specificity of the antibodies was in general found to be influenced to some extent by the presence of a second group in the antigen. The relevancy of these observations for antibodies directed against natural antigens has been noted.
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spelling pubmed-21336292008-04-18 ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS : II. ANTIGENS WITH AZOCOMPONENTS CONTAINING TWO DETERMINANT GROUPS Landsteiner, K. van der Scheer, J. J Exp Med Article Azoproteins have been prepared with azocomponents possessing two serologically active groups. On immunization with such antigens immune sera were obtained containing two separate, unrelated antibodies, each specific for one of the two groups and separable by absorption. In other cases one of the two structures was dominant, in that antibodies were formed only towards this and not towards the other grouping. The specificity of the antibodies was in general found to be influenced to some extent by the presence of a second group in the antigen. The relevancy of these observations for antibodies directed against natural antigens has been noted. The Rockefeller University Press 1938-04-30 /pmc/articles/PMC2133629/ /pubmed/19870750 Text en Copyright © Copyright, 1938, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Landsteiner, K.
van der Scheer, J.
ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS : II. ANTIGENS WITH AZOCOMPONENTS CONTAINING TWO DETERMINANT GROUPS
title ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS : II. ANTIGENS WITH AZOCOMPONENTS CONTAINING TWO DETERMINANT GROUPS
title_full ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS : II. ANTIGENS WITH AZOCOMPONENTS CONTAINING TWO DETERMINANT GROUPS
title_fullStr ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS : II. ANTIGENS WITH AZOCOMPONENTS CONTAINING TWO DETERMINANT GROUPS
title_full_unstemmed ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS : II. ANTIGENS WITH AZOCOMPONENTS CONTAINING TWO DETERMINANT GROUPS
title_short ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS : II. ANTIGENS WITH AZOCOMPONENTS CONTAINING TWO DETERMINANT GROUPS
title_sort on cross reactions of immune sera to azoproteins : ii. antigens with azocomponents containing two determinant groups
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133629/
https://www.ncbi.nlm.nih.gov/pubmed/19870750
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