THE EFFECT OF CORTICOSTERONE AND RELATED COMPOUNDS ON THE RENAL EXCRETION OF ELECTROLYTES

The sodium and chloride retaining effect of suprarenal cortical extracts and of crystalline compounds derived from the suprarenal cortex parallels their effectiveness in maintaining suprarenalectomized dogs. All of the active compounds thus far studied produce a potassium diuresis when injected into...

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Detalles Bibliográficos
Autores principales: Thorn, George W., Engel, Lewis L., Eisenberg, Harry
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1938
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133665/
https://www.ncbi.nlm.nih.gov/pubmed/19870780
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author Thorn, George W.
Engel, Lewis L.
Eisenberg, Harry
author_facet Thorn, George W.
Engel, Lewis L.
Eisenberg, Harry
author_sort Thorn, George W.
collection PubMed
description The sodium and chloride retaining effect of suprarenal cortical extracts and of crystalline compounds derived from the suprarenal cortex parallels their effectiveness in maintaining suprarenalectomized dogs. All of the active compounds thus far studied produce a potassium diuresis when injected into normal dogs. The injection of a synthetic compound, desoxy-corticosterone acetate, produced in normal dogs a very marked sodium and chloride retention and a potassium diuresis. In a suprarenalectomized dog desoxy-corticosterone acetate was substituted successfully for suprarenal cortical extract.
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spelling pubmed-21336652008-04-18 THE EFFECT OF CORTICOSTERONE AND RELATED COMPOUNDS ON THE RENAL EXCRETION OF ELECTROLYTES Thorn, George W. Engel, Lewis L. Eisenberg, Harry J Exp Med Article The sodium and chloride retaining effect of suprarenal cortical extracts and of crystalline compounds derived from the suprarenal cortex parallels their effectiveness in maintaining suprarenalectomized dogs. All of the active compounds thus far studied produce a potassium diuresis when injected into normal dogs. The injection of a synthetic compound, desoxy-corticosterone acetate, produced in normal dogs a very marked sodium and chloride retention and a potassium diuresis. In a suprarenalectomized dog desoxy-corticosterone acetate was substituted successfully for suprarenal cortical extract. The Rockefeller University Press 1938-07-31 /pmc/articles/PMC2133665/ /pubmed/19870780 Text en Copyright © Copyright, 1938, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Thorn, George W.
Engel, Lewis L.
Eisenberg, Harry
THE EFFECT OF CORTICOSTERONE AND RELATED COMPOUNDS ON THE RENAL EXCRETION OF ELECTROLYTES
title THE EFFECT OF CORTICOSTERONE AND RELATED COMPOUNDS ON THE RENAL EXCRETION OF ELECTROLYTES
title_full THE EFFECT OF CORTICOSTERONE AND RELATED COMPOUNDS ON THE RENAL EXCRETION OF ELECTROLYTES
title_fullStr THE EFFECT OF CORTICOSTERONE AND RELATED COMPOUNDS ON THE RENAL EXCRETION OF ELECTROLYTES
title_full_unstemmed THE EFFECT OF CORTICOSTERONE AND RELATED COMPOUNDS ON THE RENAL EXCRETION OF ELECTROLYTES
title_short THE EFFECT OF CORTICOSTERONE AND RELATED COMPOUNDS ON THE RENAL EXCRETION OF ELECTROLYTES
title_sort effect of corticosterone and related compounds on the renal excretion of electrolytes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133665/
https://www.ncbi.nlm.nih.gov/pubmed/19870780
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