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PRODUCTION OF EXPERIMENTAL OSTEOMYELITIS IN RABBITS BY INTRAVENOUS INJECTION OF STAPHYLOCOCCUS AUREUS

1. The conditions under which a certain strain of staphylococcus (OH 172) causes in rabbits the development of bone inflammation have been described. 2. The virulence of the strain for rabbits was markedly raised by passage through this animal species, and especially after the culture had been recov...

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Detalles Bibliográficos
Autores principales: Thompson, R. H. S., Dubos, R. J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1938
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133671/
https://www.ncbi.nlm.nih.gov/pubmed/19870782
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author Thompson, R. H. S.
Dubos, R. J.
author_facet Thompson, R. H. S.
Dubos, R. J.
author_sort Thompson, R. H. S.
collection PubMed
description 1. The conditions under which a certain strain of staphylococcus (OH 172) causes in rabbits the development of bone inflammation have been described. 2. The virulence of the strain for rabbits was markedly raised by passage through this animal species, and especially after the culture had been recovered from a bone abscess. 3. The results indicate that it is possible to produce consistently inflammation of the bones of rabbits by the mere intravenous injection of a suitable strain of staphylococcus, without resorting to any elaborate operative technique designed to localize the organisms in the bones. It appears also that the inflammatory process so produced bears a close resemblance to staphylococcal osteomyelitis as occurring in human beings.
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spelling pubmed-21336712008-04-18 PRODUCTION OF EXPERIMENTAL OSTEOMYELITIS IN RABBITS BY INTRAVENOUS INJECTION OF STAPHYLOCOCCUS AUREUS Thompson, R. H. S. Dubos, R. J. J Exp Med Article 1. The conditions under which a certain strain of staphylococcus (OH 172) causes in rabbits the development of bone inflammation have been described. 2. The virulence of the strain for rabbits was markedly raised by passage through this animal species, and especially after the culture had been recovered from a bone abscess. 3. The results indicate that it is possible to produce consistently inflammation of the bones of rabbits by the mere intravenous injection of a suitable strain of staphylococcus, without resorting to any elaborate operative technique designed to localize the organisms in the bones. It appears also that the inflammatory process so produced bears a close resemblance to staphylococcal osteomyelitis as occurring in human beings. The Rockefeller University Press 1938-07-31 /pmc/articles/PMC2133671/ /pubmed/19870782 Text en Copyright © Copyright, 1938, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Thompson, R. H. S.
Dubos, R. J.
PRODUCTION OF EXPERIMENTAL OSTEOMYELITIS IN RABBITS BY INTRAVENOUS INJECTION OF STAPHYLOCOCCUS AUREUS
title PRODUCTION OF EXPERIMENTAL OSTEOMYELITIS IN RABBITS BY INTRAVENOUS INJECTION OF STAPHYLOCOCCUS AUREUS
title_full PRODUCTION OF EXPERIMENTAL OSTEOMYELITIS IN RABBITS BY INTRAVENOUS INJECTION OF STAPHYLOCOCCUS AUREUS
title_fullStr PRODUCTION OF EXPERIMENTAL OSTEOMYELITIS IN RABBITS BY INTRAVENOUS INJECTION OF STAPHYLOCOCCUS AUREUS
title_full_unstemmed PRODUCTION OF EXPERIMENTAL OSTEOMYELITIS IN RABBITS BY INTRAVENOUS INJECTION OF STAPHYLOCOCCUS AUREUS
title_short PRODUCTION OF EXPERIMENTAL OSTEOMYELITIS IN RABBITS BY INTRAVENOUS INJECTION OF STAPHYLOCOCCUS AUREUS
title_sort production of experimental osteomyelitis in rabbits by intravenous injection of staphylococcus aureus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133671/
https://www.ncbi.nlm.nih.gov/pubmed/19870782
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