A PYOGENIC FILTERABLE AGENT IN THE ALBINO RAT

A filterable agent resembling the viruses is described. It was encountered in sarcoma 39, a propagable neoplasm of the white rat, and has now been maintained in this species for 28 passages over a period of some 7 months without appreciable loss in virulence. Its chief effect is the production of la...

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Detalles Bibliográficos
Autores principales: Woglom, William H., Warren, Joel
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1938
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133688/
https://www.ncbi.nlm.nih.gov/pubmed/19870802
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author Woglom, William H.
Warren, Joel
author_facet Woglom, William H.
Warren, Joel
author_sort Woglom, William H.
collection PubMed
description A filterable agent resembling the viruses is described. It was encountered in sarcoma 39, a propagable neoplasm of the white rat, and has now been maintained in this species for 28 passages over a period of some 7 months without appreciable loss in virulence. Its chief effect is the production of large abscesses in an animal species comparatively resistant both to viral diseases and suppuration. The white mouse is more susceptible than the white rat, the rabbit less so, and the guinea pig highly resistant. The agent has been repeatedly recovered from sarcoma 39 treated in special ways, but under the ordinary circumstances of routine transplantation it does not manifest itself. As yet there is no certainty on where it came from or how it maintains itself under natural conditions.
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spelling pubmed-21336882008-04-18 A PYOGENIC FILTERABLE AGENT IN THE ALBINO RAT Woglom, William H. Warren, Joel J Exp Med Article A filterable agent resembling the viruses is described. It was encountered in sarcoma 39, a propagable neoplasm of the white rat, and has now been maintained in this species for 28 passages over a period of some 7 months without appreciable loss in virulence. Its chief effect is the production of large abscesses in an animal species comparatively resistant both to viral diseases and suppuration. The white mouse is more susceptible than the white rat, the rabbit less so, and the guinea pig highly resistant. The agent has been repeatedly recovered from sarcoma 39 treated in special ways, but under the ordinary circumstances of routine transplantation it does not manifest itself. As yet there is no certainty on where it came from or how it maintains itself under natural conditions. The Rockefeller University Press 1938-09-30 /pmc/articles/PMC2133688/ /pubmed/19870802 Text en Copyright © Copyright, 1938, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Woglom, William H.
Warren, Joel
A PYOGENIC FILTERABLE AGENT IN THE ALBINO RAT
title A PYOGENIC FILTERABLE AGENT IN THE ALBINO RAT
title_full A PYOGENIC FILTERABLE AGENT IN THE ALBINO RAT
title_fullStr A PYOGENIC FILTERABLE AGENT IN THE ALBINO RAT
title_full_unstemmed A PYOGENIC FILTERABLE AGENT IN THE ALBINO RAT
title_short A PYOGENIC FILTERABLE AGENT IN THE ALBINO RAT
title_sort pyogenic filterable agent in the albino rat
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133688/
https://www.ncbi.nlm.nih.gov/pubmed/19870802
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