INTRAPERITONEAL AND INTRACEREBRAL ROUTES IN SERUM PROTECTION TESTS WITH THE VIRUS OF EQUINE ENCEPHALOMYELITIS : II. MECHANISM UNDERLYING THE DIFFERENCE IN PROTECTIVE POWER BY THE TWO ROUTES

Minute amounts of antiserum injected intraperitoneally protect against large doses of equine encephalomyelitis virus given intramuscularly or intraperitoneally in 12 to 15 day old mice. Antiserum given intraperitoneally with virus intracerebrally or intranasally results in little or no protection. T...

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Detalles Bibliográficos
Autores principales: Olitsky, Peter K., Harford, Carl G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1938
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133696/
https://www.ncbi.nlm.nih.gov/pubmed/19870815
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author Olitsky, Peter K.
Harford, Carl G.
author_facet Olitsky, Peter K.
Harford, Carl G.
author_sort Olitsky, Peter K.
collection PubMed
description Minute amounts of antiserum injected intraperitoneally protect against large doses of equine encephalomyelitis virus given intramuscularly or intraperitoneally in 12 to 15 day old mice. Antiserum given intraperitoneally with virus intracerebrally or intranasally results in little or no protection. These phenomena occur as well when serum-virus mixtures are injected at the different sites. The marked variation of the protective capacity of antiserum as thus displayed would appear to be dependent upon the differing pathways of progression of the virus from the site of injection to the central nervous system.
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spelling pubmed-21336962008-04-18 INTRAPERITONEAL AND INTRACEREBRAL ROUTES IN SERUM PROTECTION TESTS WITH THE VIRUS OF EQUINE ENCEPHALOMYELITIS : II. MECHANISM UNDERLYING THE DIFFERENCE IN PROTECTIVE POWER BY THE TWO ROUTES Olitsky, Peter K. Harford, Carl G. J Exp Med Article Minute amounts of antiserum injected intraperitoneally protect against large doses of equine encephalomyelitis virus given intramuscularly or intraperitoneally in 12 to 15 day old mice. Antiserum given intraperitoneally with virus intracerebrally or intranasally results in little or no protection. These phenomena occur as well when serum-virus mixtures are injected at the different sites. The marked variation of the protective capacity of antiserum as thus displayed would appear to be dependent upon the differing pathways of progression of the virus from the site of injection to the central nervous system. The Rockefeller University Press 1938-10-31 /pmc/articles/PMC2133696/ /pubmed/19870815 Text en Copyright © Copyright, 1938, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Olitsky, Peter K.
Harford, Carl G.
INTRAPERITONEAL AND INTRACEREBRAL ROUTES IN SERUM PROTECTION TESTS WITH THE VIRUS OF EQUINE ENCEPHALOMYELITIS : II. MECHANISM UNDERLYING THE DIFFERENCE IN PROTECTIVE POWER BY THE TWO ROUTES
title INTRAPERITONEAL AND INTRACEREBRAL ROUTES IN SERUM PROTECTION TESTS WITH THE VIRUS OF EQUINE ENCEPHALOMYELITIS : II. MECHANISM UNDERLYING THE DIFFERENCE IN PROTECTIVE POWER BY THE TWO ROUTES
title_full INTRAPERITONEAL AND INTRACEREBRAL ROUTES IN SERUM PROTECTION TESTS WITH THE VIRUS OF EQUINE ENCEPHALOMYELITIS : II. MECHANISM UNDERLYING THE DIFFERENCE IN PROTECTIVE POWER BY THE TWO ROUTES
title_fullStr INTRAPERITONEAL AND INTRACEREBRAL ROUTES IN SERUM PROTECTION TESTS WITH THE VIRUS OF EQUINE ENCEPHALOMYELITIS : II. MECHANISM UNDERLYING THE DIFFERENCE IN PROTECTIVE POWER BY THE TWO ROUTES
title_full_unstemmed INTRAPERITONEAL AND INTRACEREBRAL ROUTES IN SERUM PROTECTION TESTS WITH THE VIRUS OF EQUINE ENCEPHALOMYELITIS : II. MECHANISM UNDERLYING THE DIFFERENCE IN PROTECTIVE POWER BY THE TWO ROUTES
title_short INTRAPERITONEAL AND INTRACEREBRAL ROUTES IN SERUM PROTECTION TESTS WITH THE VIRUS OF EQUINE ENCEPHALOMYELITIS : II. MECHANISM UNDERLYING THE DIFFERENCE IN PROTECTIVE POWER BY THE TWO ROUTES
title_sort intraperitoneal and intracerebral routes in serum protection tests with the virus of equine encephalomyelitis : ii. mechanism underlying the difference in protective power by the two routes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133696/
https://www.ncbi.nlm.nih.gov/pubmed/19870815
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AT harfordcarlg intraperitonealandintracerebralroutesinserumprotectiontestswiththevirusofequineencephalomyelitisiimechanismunderlyingthedifferenceinprotectivepowerbythetworoutes

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