CELLULAR REACTIONS TO DEFATTED TUBERCLE BACILLI AND THEIR PRODUCTS

The cellular reactions to defatted tubercle bacilli are complex and like those to heat-killed whole tubercle bacilli. The firmly bound lipid, when removed from these organisms, is non-acid-fast; it contains an hydroxy acid which is acid-fast and a polysaccharide, which is not. This hydroxy acid give...

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Detalles Bibliográficos
Autores principales: Sabin, Florence R., Joyner, Austin L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1938
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133716/
https://www.ncbi.nlm.nih.gov/pubmed/19870822
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author Sabin, Florence R.
Joyner, Austin L.
author_facet Sabin, Florence R.
Joyner, Austin L.
author_sort Sabin, Florence R.
collection PubMed
description The cellular reactions to defatted tubercle bacilli are complex and like those to heat-killed whole tubercle bacilli. The firmly bound lipid, when removed from these organisms, is non-acid-fast; it contains an hydroxy acid which is acid-fast and a polysaccharide, which is not. This hydroxy acid gives rise to foreign body giant cells and the tissues eventually become infiltrated with eosinophiles. The polysaccharides, both from the defatted bacilli and from the unfilterable lipid, call neutrophiles from the blood stream. The reactions to the unfilterable lipid include those of both its constituents.
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spelling pubmed-21337162008-04-18 CELLULAR REACTIONS TO DEFATTED TUBERCLE BACILLI AND THEIR PRODUCTS Sabin, Florence R. Joyner, Austin L. J Exp Med Article The cellular reactions to defatted tubercle bacilli are complex and like those to heat-killed whole tubercle bacilli. The firmly bound lipid, when removed from these organisms, is non-acid-fast; it contains an hydroxy acid which is acid-fast and a polysaccharide, which is not. This hydroxy acid gives rise to foreign body giant cells and the tissues eventually become infiltrated with eosinophiles. The polysaccharides, both from the defatted bacilli and from the unfilterable lipid, call neutrophiles from the blood stream. The reactions to the unfilterable lipid include those of both its constituents. The Rockefeller University Press 1938-10-31 /pmc/articles/PMC2133716/ /pubmed/19870822 Text en Copyright © Copyright, 1938, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Sabin, Florence R.
Joyner, Austin L.
CELLULAR REACTIONS TO DEFATTED TUBERCLE BACILLI AND THEIR PRODUCTS
title CELLULAR REACTIONS TO DEFATTED TUBERCLE BACILLI AND THEIR PRODUCTS
title_full CELLULAR REACTIONS TO DEFATTED TUBERCLE BACILLI AND THEIR PRODUCTS
title_fullStr CELLULAR REACTIONS TO DEFATTED TUBERCLE BACILLI AND THEIR PRODUCTS
title_full_unstemmed CELLULAR REACTIONS TO DEFATTED TUBERCLE BACILLI AND THEIR PRODUCTS
title_short CELLULAR REACTIONS TO DEFATTED TUBERCLE BACILLI AND THEIR PRODUCTS
title_sort cellular reactions to defatted tubercle bacilli and their products
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133716/
https://www.ncbi.nlm.nih.gov/pubmed/19870822
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AT joyneraustinl cellularreactionstodefattedtuberclebacilliandtheirproducts

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