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HEREDITARY BRACHYDACTYLIA AND ALLIED ABNORMALITIES IN THE RABBIT
A series of deformities in the rabbit ranging from brachydactylia to acheiropodia have been described. Experimental breeding demonstrated that the occurrence of the deformities was determined by simple recessive hereditary factors and that the various types were genetically related and were not dist...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1939
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133737/ https://www.ncbi.nlm.nih.gov/pubmed/19870848 |
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author | Greene, Harry S. N. Saxton, John A. |
author_facet | Greene, Harry S. N. Saxton, John A. |
author_sort | Greene, Harry S. N. |
collection | PubMed |
description | A series of deformities in the rabbit ranging from brachydactylia to acheiropodia have been described. Experimental breeding demonstrated that the occurrence of the deformities was determined by simple recessive hereditary factors and that the various types were genetically related and were not distinct hereditary entities. Embryological investigation showed the first abnormal change was a dilatation of blood vessels in affected buds. This was followed by hemorrhage and necrosis of the parts involved. Sloughing subsequently occurred, and the deformity was completely expressed by the 25th day of fetal life. |
format | Text |
id | pubmed-2133737 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1939 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21337372008-04-18 HEREDITARY BRACHYDACTYLIA AND ALLIED ABNORMALITIES IN THE RABBIT Greene, Harry S. N. Saxton, John A. J Exp Med Article A series of deformities in the rabbit ranging from brachydactylia to acheiropodia have been described. Experimental breeding demonstrated that the occurrence of the deformities was determined by simple recessive hereditary factors and that the various types were genetically related and were not distinct hereditary entities. Embryological investigation showed the first abnormal change was a dilatation of blood vessels in affected buds. This was followed by hemorrhage and necrosis of the parts involved. Sloughing subsequently occurred, and the deformity was completely expressed by the 25th day of fetal life. The Rockefeller University Press 1939-01-31 /pmc/articles/PMC2133737/ /pubmed/19870848 Text en Copyright © Copyright, 1939, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Greene, Harry S. N. Saxton, John A. HEREDITARY BRACHYDACTYLIA AND ALLIED ABNORMALITIES IN THE RABBIT |
title | HEREDITARY BRACHYDACTYLIA AND ALLIED ABNORMALITIES IN THE RABBIT |
title_full | HEREDITARY BRACHYDACTYLIA AND ALLIED ABNORMALITIES IN THE RABBIT |
title_fullStr | HEREDITARY BRACHYDACTYLIA AND ALLIED ABNORMALITIES IN THE RABBIT |
title_full_unstemmed | HEREDITARY BRACHYDACTYLIA AND ALLIED ABNORMALITIES IN THE RABBIT |
title_short | HEREDITARY BRACHYDACTYLIA AND ALLIED ABNORMALITIES IN THE RABBIT |
title_sort | hereditary brachydactylia and allied abnormalities in the rabbit |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133737/ https://www.ncbi.nlm.nih.gov/pubmed/19870848 |
work_keys_str_mv | AT greeneharrysn hereditarybrachydactyliaandalliedabnormalitiesintherabbit AT saxtonjohna hereditarybrachydactyliaandalliedabnormalitiesintherabbit |