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STUDIES ON ANTIBACTERIAL IMMUNITY INDUCED BY ARTIFICIAL ANTIGENS : I. IMMUNITY TO EXPERIMENTAL PNEUMOCOCCAL INFECTION WITH AN ANTIGEN CONTAINING CELLOBIURONIC ACID

1. An artificial antigen containing the azobenzyl glycoside of cellobiuronic acid gives rise in rabbits to antibodies which: (a) give the Neufeld reaction and agglutinate Type III pneumococci, (b) confer passive protection on mice against infection with Types II, III, and VIII pneumococci. 2. Rabbit...

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Detalles Bibliográficos
Autor principal: Goebel, Walther F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1939
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133744/
https://www.ncbi.nlm.nih.gov/pubmed/19870851
Descripción
Sumario:1. An artificial antigen containing the azobenzyl glycoside of cellobiuronic acid gives rise in rabbits to antibodies which: (a) give the Neufeld reaction and agglutinate Type III pneumococci, (b) confer passive protection on mice against infection with Types II, III, and VIII pneumococci. 2. Rabbits immunized with the artificial cellobiuronic acid antigen acquire active resistance to infection with virulent Type III pneumococci. 3. The antibodies evoked by an antigen containing the azobenzyl glycoside of cellobiose exhibit none of these phenomena.