A SOLUBLE ANTIGEN OF LYMPHOCYTIC CHORIOMENINGITIS : I. SEPARATION OF SOLUBLE ANTIGEN FROM VIRUS

The virus of lymphocytic choriomeningitis can be sedimented in the ultracentrifuge and washed repeatedly; the virus retains its activity provided that a small amount of normal serum is present in the diluent. A soluble substance capable of fixing complement in the presence of immune serum can be sep...

Descripción completa

Detalles Bibliográficos
Autores principales: Smadel, J. E., Baird, R. D., Wall, M. J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1939
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133775/
https://www.ncbi.nlm.nih.gov/pubmed/19870890
Descripción
Sumario:The virus of lymphocytic choriomeningitis can be sedimented in the ultracentrifuge and washed repeatedly; the virus retains its activity provided that a small amount of normal serum is present in the diluent. A soluble substance capable of fixing complement in the presence of immune serum can be separated from the virus. Washed virus fixes complement poorly. The serologically specific soluble antigen is widely distributed in tissues of infected guinea pigs, mice, and monkeys.

Ejemplares similares