A SOLUBLE ANTIGEN OF LYMPHOCYTIC CHORIOMENINGITIS : I. SEPARATION OF SOLUBLE ANTIGEN FROM VIRUS

The virus of lymphocytic choriomeningitis can be sedimented in the ultracentrifuge and washed repeatedly; the virus retains its activity provided that a small amount of normal serum is present in the diluent. A soluble substance capable of fixing complement in the presence of immune serum can be sep...

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Detalles Bibliográficos
Autores principales: Smadel, J. E., Baird, R. D., Wall, M. J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1939
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133775/
https://www.ncbi.nlm.nih.gov/pubmed/19870890
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author Smadel, J. E.
Baird, R. D.
Wall, M. J.
author_facet Smadel, J. E.
Baird, R. D.
Wall, M. J.
author_sort Smadel, J. E.
collection PubMed
description The virus of lymphocytic choriomeningitis can be sedimented in the ultracentrifuge and washed repeatedly; the virus retains its activity provided that a small amount of normal serum is present in the diluent. A soluble substance capable of fixing complement in the presence of immune serum can be separated from the virus. Washed virus fixes complement poorly. The serologically specific soluble antigen is widely distributed in tissues of infected guinea pigs, mice, and monkeys.
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spelling pubmed-21337752008-04-18 A SOLUBLE ANTIGEN OF LYMPHOCYTIC CHORIOMENINGITIS : I. SEPARATION OF SOLUBLE ANTIGEN FROM VIRUS Smadel, J. E. Baird, R. D. Wall, M. J. J Exp Med Article The virus of lymphocytic choriomeningitis can be sedimented in the ultracentrifuge and washed repeatedly; the virus retains its activity provided that a small amount of normal serum is present in the diluent. A soluble substance capable of fixing complement in the presence of immune serum can be separated from the virus. Washed virus fixes complement poorly. The serologically specific soluble antigen is widely distributed in tissues of infected guinea pigs, mice, and monkeys. The Rockefeller University Press 1939-06-30 /pmc/articles/PMC2133775/ /pubmed/19870890 Text en Copyright © Copyright, 1939, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Smadel, J. E.
Baird, R. D.
Wall, M. J.
A SOLUBLE ANTIGEN OF LYMPHOCYTIC CHORIOMENINGITIS : I. SEPARATION OF SOLUBLE ANTIGEN FROM VIRUS
title A SOLUBLE ANTIGEN OF LYMPHOCYTIC CHORIOMENINGITIS : I. SEPARATION OF SOLUBLE ANTIGEN FROM VIRUS
title_full A SOLUBLE ANTIGEN OF LYMPHOCYTIC CHORIOMENINGITIS : I. SEPARATION OF SOLUBLE ANTIGEN FROM VIRUS
title_fullStr A SOLUBLE ANTIGEN OF LYMPHOCYTIC CHORIOMENINGITIS : I. SEPARATION OF SOLUBLE ANTIGEN FROM VIRUS
title_full_unstemmed A SOLUBLE ANTIGEN OF LYMPHOCYTIC CHORIOMENINGITIS : I. SEPARATION OF SOLUBLE ANTIGEN FROM VIRUS
title_short A SOLUBLE ANTIGEN OF LYMPHOCYTIC CHORIOMENINGITIS : I. SEPARATION OF SOLUBLE ANTIGEN FROM VIRUS
title_sort soluble antigen of lymphocytic choriomeningitis : i. separation of soluble antigen from virus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133775/
https://www.ncbi.nlm.nih.gov/pubmed/19870890
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