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ARTIFICIAL MAINTENANCE MEDIA FOR CELL AND ORGAN CULTIVATION : II. THE CULTIVATION OF ORGANS IN ARTIFICIAL MEDIA
Experiments have been described in which organs cultivated in the Lindbergh apparatus have been kept alive in artificial media for periods ranging from 3 days to 3 weeks, with life continuing in portions of some glands for from 35 to 62 days. The media used varied in composition from very simple and...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1939
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133776/ https://www.ncbi.nlm.nih.gov/pubmed/19870888 |
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author | Baker, Lillian E. Carrel, Alexis |
author_facet | Baker, Lillian E. Carrel, Alexis |
author_sort | Baker, Lillian E. |
collection | PubMed |
description | Experiments have been described in which organs cultivated in the Lindbergh apparatus have been kept alive in artificial media for periods ranging from 3 days to 3 weeks, with life continuing in portions of some glands for from 35 to 62 days. The media used varied in composition from very simple and inexpensive ones in which some serum was used to a rather complex medium containing only that negligible amount of serum that is necessary as a solvent for vitamin A. The experiments performed demonstrate that artificial media can be used for organ cultivation, thus making it possible to study the behavior of human organs; to control the composition of the media at will; and to reduce the cost of experimentation. |
format | Text |
id | pubmed-2133776 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1939 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21337762008-04-18 ARTIFICIAL MAINTENANCE MEDIA FOR CELL AND ORGAN CULTIVATION : II. THE CULTIVATION OF ORGANS IN ARTIFICIAL MEDIA Baker, Lillian E. Carrel, Alexis J Exp Med Article Experiments have been described in which organs cultivated in the Lindbergh apparatus have been kept alive in artificial media for periods ranging from 3 days to 3 weeks, with life continuing in portions of some glands for from 35 to 62 days. The media used varied in composition from very simple and inexpensive ones in which some serum was used to a rather complex medium containing only that negligible amount of serum that is necessary as a solvent for vitamin A. The experiments performed demonstrate that artificial media can be used for organ cultivation, thus making it possible to study the behavior of human organs; to control the composition of the media at will; and to reduce the cost of experimentation. The Rockefeller University Press 1939-06-30 /pmc/articles/PMC2133776/ /pubmed/19870888 Text en Copyright © Copyright, 1939, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Baker, Lillian E. Carrel, Alexis ARTIFICIAL MAINTENANCE MEDIA FOR CELL AND ORGAN CULTIVATION : II. THE CULTIVATION OF ORGANS IN ARTIFICIAL MEDIA |
title | ARTIFICIAL MAINTENANCE MEDIA FOR CELL AND ORGAN CULTIVATION : II. THE CULTIVATION OF ORGANS IN ARTIFICIAL MEDIA |
title_full | ARTIFICIAL MAINTENANCE MEDIA FOR CELL AND ORGAN CULTIVATION : II. THE CULTIVATION OF ORGANS IN ARTIFICIAL MEDIA |
title_fullStr | ARTIFICIAL MAINTENANCE MEDIA FOR CELL AND ORGAN CULTIVATION : II. THE CULTIVATION OF ORGANS IN ARTIFICIAL MEDIA |
title_full_unstemmed | ARTIFICIAL MAINTENANCE MEDIA FOR CELL AND ORGAN CULTIVATION : II. THE CULTIVATION OF ORGANS IN ARTIFICIAL MEDIA |
title_short | ARTIFICIAL MAINTENANCE MEDIA FOR CELL AND ORGAN CULTIVATION : II. THE CULTIVATION OF ORGANS IN ARTIFICIAL MEDIA |
title_sort | artificial maintenance media for cell and organ cultivation : ii. the cultivation of organs in artificial media |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133776/ https://www.ncbi.nlm.nih.gov/pubmed/19870888 |
work_keys_str_mv | AT bakerlilliane artificialmaintenancemediaforcellandorgancultivationiithecultivationoforgansinartificialmedia AT carrelalexis artificialmaintenancemediaforcellandorgancultivationiithecultivationoforgansinartificialmedia |