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Targeted Disruption of Decorin Leads to Abnormal Collagen Fibril Morphology and Skin Fragility
Decorin is a member of the expanding group of widely distributed small leucine-rich proteoglycans that are expected to play important functions in tissue assembly. We report that mice harboring a targeted disruption of the decorin gene are viable but have fragile skin with markedly reduced tensile s...
Autores principales: | Danielson, Keith G., Baribault, Helene, Holmes, David F., Graham, Helen, Kadler, Karl E., Iozzo, Renato V. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134287/ https://www.ncbi.nlm.nih.gov/pubmed/9024701 |
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