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Genome-Wide Analysis of Rad52 Foci Reveals Diverse Mechanisms Impacting Recombination
To investigate the DNA damage response, we undertook a genome-wide study in Saccharomyces cerevisiae and identified 86 gene deletions that lead to increased levels of spontaneous Rad52 foci in proliferating diploid cells. More than half of the genes are conserved across species ranging from yeast to...
Autores principales: | Alvaro, David, Lisby, Michael, Rothstein, Rodney |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134942/ https://www.ncbi.nlm.nih.gov/pubmed/18085829 http://dx.doi.org/10.1371/journal.pgen.0030228 |
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