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Genome-Wide Analysis of Rad52 Foci Reveals Diverse Mechanisms Impacting Recombination

To investigate the DNA damage response, we undertook a genome-wide study in Saccharomyces cerevisiae and identified 86 gene deletions that lead to increased levels of spontaneous Rad52 foci in proliferating diploid cells. More than half of the genes are conserved across species ranging from yeast to...

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Detalles Bibliográficos
Autores principales: Alvaro, David, Lisby, Michael, Rothstein, Rodney
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134942/
https://www.ncbi.nlm.nih.gov/pubmed/18085829
http://dx.doi.org/10.1371/journal.pgen.0030228

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