Cargando…

A RNA Interference Screen Identifies the Protein Phosphatase 2A Subunit PR55γ as a Stress-Sensitive Inhibitor of c-SRC

Protein Phosphatase type 2A (PP2A) represents a family of holoenzyme complexes with diverse biological activities. Specific holoenzyme complexes are thought to be deregulated during oncogenic transformation and oncogene-induced signaling. Since most studies on the role of this phosphatase family hav...

Descripción completa

Detalles Bibliográficos
Autores principales:	Eichhorn, Pieter J. A, Creyghton, Menno P, Wilhelmsen, Kevin, van Dam, Hans, Bernards, René
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134945/ https://www.ncbi.nlm.nih.gov/pubmed/18069897 http://dx.doi.org/10.1371/journal.pgen.0030218

Ejemplares similares

p53/FBXL20 axis negatively regulates the protein stability of PR55α, a regulatory subunit of PP2A Ser/Thr phosphatase
por: Madduri, Lepakshe S.V., et al.
Publicado: (2021)

Hypercontractile cardiac phenotype in mice overexpressing the regulatory subunit PR72 of protein phosphatase 2A
por: Herting, Julius R., et al.
Publicado: (2023)

CERN Opendays 2019 - PR-55
por: Chrul, Anna, et al.
Publicado: (2019)

Structural and Biochemical Characterization of Human PR70 in Isolation and in Complex with the Scaffolding Subunit of Protein Phosphatase 2A
por: Dovega, Rebecca, et al.
Publicado: (2014)

Protein interactomes of protein phosphatase 2A B55 regulatory subunits reveal B55-mediated regulation of replication protein A under replication stress
por: Wang, Feifei, et al.
Publicado: (2018)

Protein phosphatase subunit G5PR is needed for inhibition of B cell receptor–induced apoptosis
por: Xing, Yan, et al.
Publicado: (2005)

Diversity in genomic organisation, developmental regulation and distribution of the murine PR72/B" subunits of protein phosphatase 2A
por: Zwaenepoel, Karen, et al.
Publicado: (2008)

Protein phosphatase 2A regulatory subunit B55α functions in mouse oocyte maturation and early embryonic development
por: Liang, Shuang, et al.
Publicado: (2017)

Interference of PR3-ANCA with the enzymatic activity of PR3
por: Rarok, AA, et al.
Publicado: (2002)

Regulation of synaptojanin 2 5′-phosphatase activity by Src
por: Chuang, Yayu, et al.
Publicado: (2012)

Common themes in PrP signaling: the Src remains the same
por: Ochs, Katharina, et al.
Publicado: (2014)

PR55α regulatory subunit of PP2A inhibits the MOB1/LATS cascade and activates YAP in pancreatic cancer cells
por: Hein, Ashley L., et al.
Publicado: (2019)

HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130
por: Göder, Anja, et al.
Publicado: (2018)

Linkage Mapping of the Bra, Brb and Brg Genes for Rat Protein Phosphatase 2A 55 kDa B‐Regulatory Subunit Isotypes
por: Yamada, Shin, et al.
Publicado: (1998)

The thermodynamics of Pr55(Gag)-RNA interaction regulate the assembly of HIV
por: Tanwar, Hanumant S., et al.
Publicado: (2017)

Transcriptional Dynamics at Brain Enhancers: from Functional Specialization to Neurodegeneration
por: Vermunt, Marit W., et al.
Publicado: (2016)

Molecular Cloning of the Genes Encoding the PR55/Bβ/δ Regulatory Subunits for PP-2A and Analysis of Their Functions in Regulating Development of Goldfish, Carassius auratus
por: Zhao, Jun-Qiong, et al.
Publicado: (2010)

Src Homology 2 Protein Tyrosine Phosphatase (SHPTP2)/Src Homology 2 Phosphatase 2 (SHP2) Tyrosine Phosphatase Is a Positive Regulator of the Interleukin 5 Receptor Signal Transduction Pathways Leading to the Prolongation of Eosinophil Survival
por: Pazdrak, Konrad, et al.
Publicado: (1997)

Recombinant α- β- and γ-Synucleins Stimulate Protein Phosphatase 2A Catalytic Subunit Activity in Cell Free Assays
por: Lek, Sovanarak, et al.
Publicado: (2017)

A Pragmatic Randomized Controlled Trial to Increase PrEP Uptake for HIV Prevention: 55-Week Results From PrEPChicago
por: Schneider, John A., et al.
Publicado: (2021)

Alkaline phosphatase interference in immuno-enzymatic assays
por: Oğuz, Osman, et al.
Publicado: (2022)

Src homology domain-containing phosphatase 2 suppresses cellular senescence in glioblastoma
por: Sturla, L-M, et al.
Publicado: (2011)

Involvement of Src kinases and PLCγ2 in clot retraction
por: Suzuki-Inoue, Katsue, et al.
Publicado: (2007)

Protein Phosphatase 1 β Paralogs Encode the Zebrafish Myosin Phosphatase Catalytic Subunit
por: Jayashankar, Vaishali, et al.
Publicado: (2013)

Immunoproteasome Assembly: Cooperative Incorporation of Interferon γ (IFN-γ)–inducible Subunits
por: Griffin, Thomas A., et al.
Publicado: (1998)

Dual Regulation of the Mitotic Exit Network (MEN) by PP2A-Cdc55 Phosphatase
por: Baro, Barbara, et al.
Publicado: (2013)

Structural, enzymatic and spatiotemporal regulation of PP2A-B55 phosphatase in the control of mitosis
por: Lacroix, Benjamin, et al.
Publicado: (2022)

Expression of a protein tyrosine phosphatase in normal and v-src- transformed mouse 3T3 fibroblasts
Publicado: (1992)

Phosphorylated Peptide Derived from the Myosin Phosphatase Target Subunit Is a Novel Inhibitor of Protein Phosphatase-1
por: Kónya, Zoltán, et al.
Publicado: (2023)

Mechanisms of the Scaffold Subunit in Facilitating Protein Phosphatase 2A Methylation
por: Stanevich, Vitali, et al.
Publicado: (2014)

Class II Transactivator (CIITA) Enhances Cytoplasmic Processing of HIV-1 Pr55Gag
por: Porter, Kristen A., et al.
Publicado: (2010)

Src-homology protein tyrosine phosphatase-1 agonist, SC-43, reduces liver fibrosis
por: Su, Tung-Hung, et al.
Publicado: (2017)

A functional interaction between liprin-α1 and B56γ regulatory subunit of protein phosphatase 2A supports tumor cell motility
por: Ripamonti, Marta, et al.
Publicado: (2022)

Hepatitis C virus infection inhibits a Src-kinase regulatory phosphatase and reduces T cell activation in vivo
por: Bhattarai, Nirjal, et al.
Publicado: (2017)

Catalytic Subunit 1 of Protein Phosphatase 2A Is a Subunit of the STRIPAK Complex and Governs Fungal Sexual Development
por: Beier, Anna, et al.
Publicado: (2016)

Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development
por: Panicker, Nikita, et al.
Publicado: (2020)

Activation of Myosin Phosphatase Targeting Subunit by Mitosis-specific Phosphorylation
por: Totsukawa, Go, et al.
Publicado: (1999)

Differential regulation of the androgen receptor by protein phosphatase regulatory subunits
por: Grey, James, et al.
Publicado: (2017)

The role of phosphoprotein phosphatases catalytic subunit genes in pancreatic cancer
por: Hang, Junjie, et al.
Publicado: (2021)

Hypomethylation of the promoter of the catalytic subunit of protein phosphatase 2A in response to hyperglycemia
por: Tros, Fabiola, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_coh1oetilg6rr7cf3j1i6l1684