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PERMEABILITY OF THE HUMAN PLACENTA TO ANTIBODIES : A QUANTITATIVE STUDY

The ratio of the titers of various antibodies, namely, hemagglutinins and syphilitic reagin, in the maternal blood to that of the corresponding antibody in the cord blood was found to be relatively constant, falling somewhere between 8 and 16. This figure may be considered the "index of permeab...

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Detalles Bibliográficos
Autores principales: Wiener, Alexander S., Silverman, I. Jerome
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1940
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135006/
https://www.ncbi.nlm.nih.gov/pubmed/19870941
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author Wiener, Alexander S.
Silverman, I. Jerome
author_facet Wiener, Alexander S.
Silverman, I. Jerome
author_sort Wiener, Alexander S.
collection PubMed
description The ratio of the titers of various antibodies, namely, hemagglutinins and syphilitic reagin, in the maternal blood to that of the corresponding antibody in the cord blood was found to be relatively constant, falling somewhere between 8 and 16. This figure may be considered the "index of permeability" of human placenta to antibodies, or the coefficient of distribution of antibodies between maternal and cord blood. The possible application of these findings to the study of the placental permeability to sensitizing antibodies (or reagins) is discussed.
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spelling pubmed-21350062008-04-18 PERMEABILITY OF THE HUMAN PLACENTA TO ANTIBODIES : A QUANTITATIVE STUDY Wiener, Alexander S. Silverman, I. Jerome J Exp Med Article The ratio of the titers of various antibodies, namely, hemagglutinins and syphilitic reagin, in the maternal blood to that of the corresponding antibody in the cord blood was found to be relatively constant, falling somewhere between 8 and 16. This figure may be considered the "index of permeability" of human placenta to antibodies, or the coefficient of distribution of antibodies between maternal and cord blood. The possible application of these findings to the study of the placental permeability to sensitizing antibodies (or reagins) is discussed. The Rockefeller University Press 1940-01-01 /pmc/articles/PMC2135006/ /pubmed/19870941 Text en Copyright © Copyright, 1940, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Wiener, Alexander S.
Silverman, I. Jerome
PERMEABILITY OF THE HUMAN PLACENTA TO ANTIBODIES : A QUANTITATIVE STUDY
title PERMEABILITY OF THE HUMAN PLACENTA TO ANTIBODIES : A QUANTITATIVE STUDY
title_full PERMEABILITY OF THE HUMAN PLACENTA TO ANTIBODIES : A QUANTITATIVE STUDY
title_fullStr PERMEABILITY OF THE HUMAN PLACENTA TO ANTIBODIES : A QUANTITATIVE STUDY
title_full_unstemmed PERMEABILITY OF THE HUMAN PLACENTA TO ANTIBODIES : A QUANTITATIVE STUDY
title_short PERMEABILITY OF THE HUMAN PLACENTA TO ANTIBODIES : A QUANTITATIVE STUDY
title_sort permeability of the human placenta to antibodies : a quantitative study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135006/
https://www.ncbi.nlm.nih.gov/pubmed/19870941
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