THE SYNERGISM OF HUMAN INFLUENZA AND CANINE DISTEMPER VIRUSES IN FERRETS

The infections produced in ferrets by human influenza virus and canine distemper virus were studied. Cross immunity and cross neutralization tests showed that these two viruses were not related antigenically. Ferrets infected with influenza virus alone rapidly produced considerable quantities of neu...

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Detalles Bibliográficos
Autores principales: Horsfall, Frank L., Lennette, Edwin H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1940
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135063/
https://www.ncbi.nlm.nih.gov/pubmed/19871021
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author Horsfall, Frank L.
Lennette, Edwin H.
author_facet Horsfall, Frank L.
Lennette, Edwin H.
author_sort Horsfall, Frank L.
collection PubMed
description The infections produced in ferrets by human influenza virus and canine distemper virus were studied. Cross immunity and cross neutralization tests showed that these two viruses were not related antigenically. Ferrets infected with influenza virus alone rapidly produced considerable quantities of neutralizing antibodies, and after the 6th day virus was not demonstrable in their lungs. Ferrets infected with both influenza and distemper viruses simultaneously produced but small amounts of neutralizing antibody, and influenza virus persisted in undiminished concentration in their lungs throughout the course of the infection.
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spelling pubmed-21350632008-04-18 THE SYNERGISM OF HUMAN INFLUENZA AND CANINE DISTEMPER VIRUSES IN FERRETS Horsfall, Frank L. Lennette, Edwin H. J Exp Med Article The infections produced in ferrets by human influenza virus and canine distemper virus were studied. Cross immunity and cross neutralization tests showed that these two viruses were not related antigenically. Ferrets infected with influenza virus alone rapidly produced considerable quantities of neutralizing antibodies, and after the 6th day virus was not demonstrable in their lungs. Ferrets infected with both influenza and distemper viruses simultaneously produced but small amounts of neutralizing antibody, and influenza virus persisted in undiminished concentration in their lungs throughout the course of the infection. The Rockefeller University Press 1940-08-31 /pmc/articles/PMC2135063/ /pubmed/19871021 Text en Copyright © Copyright, 1940, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Horsfall, Frank L.
Lennette, Edwin H.
THE SYNERGISM OF HUMAN INFLUENZA AND CANINE DISTEMPER VIRUSES IN FERRETS
title THE SYNERGISM OF HUMAN INFLUENZA AND CANINE DISTEMPER VIRUSES IN FERRETS
title_full THE SYNERGISM OF HUMAN INFLUENZA AND CANINE DISTEMPER VIRUSES IN FERRETS
title_fullStr THE SYNERGISM OF HUMAN INFLUENZA AND CANINE DISTEMPER VIRUSES IN FERRETS
title_full_unstemmed THE SYNERGISM OF HUMAN INFLUENZA AND CANINE DISTEMPER VIRUSES IN FERRETS
title_short THE SYNERGISM OF HUMAN INFLUENZA AND CANINE DISTEMPER VIRUSES IN FERRETS
title_sort synergism of human influenza and canine distemper viruses in ferrets
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135063/
https://www.ncbi.nlm.nih.gov/pubmed/19871021
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