STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS : VII. SKIN SENSITIZATION BY INTRAPERITONEAL INJECTIONS

A method has been described by which sensitization to a simple chemical, picryl chloride (2:4:6 trinitrochlorobenzene), can be satisfactorily attained by means of intraperitoneal injection of the compound when killed tubercle bacilli suspended in paraffin oil were used as adjuvant. Sensitivity of th...

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Detalles Bibliográficos
Autores principales: Landsteiner, K., Chase, M. W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1940
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135072/
https://www.ncbi.nlm.nih.gov/pubmed/19870959
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author Landsteiner, K.
Chase, M. W.
author_facet Landsteiner, K.
Chase, M. W.
author_sort Landsteiner, K.
collection PubMed
description A method has been described by which sensitization to a simple chemical, picryl chloride (2:4:6 trinitrochlorobenzene), can be satisfactorily attained by means of intraperitoneal injection of the compound when killed tubercle bacilli suspended in paraffin oil were used as adjuvant. Sensitivity of the contact dermatitis type results therefrom. It follows that although skin sensitization of this type is most easily obtained by dermal application this route of administration is no necessary condition for such sensitivity.
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spelling pubmed-21350722008-04-18 STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS : VII. SKIN SENSITIZATION BY INTRAPERITONEAL INJECTIONS Landsteiner, K. Chase, M. W. J Exp Med Article A method has been described by which sensitization to a simple chemical, picryl chloride (2:4:6 trinitrochlorobenzene), can be satisfactorily attained by means of intraperitoneal injection of the compound when killed tubercle bacilli suspended in paraffin oil were used as adjuvant. Sensitivity of the contact dermatitis type results therefrom. It follows that although skin sensitization of this type is most easily obtained by dermal application this route of administration is no necessary condition for such sensitivity. The Rockefeller University Press 1940-01-31 /pmc/articles/PMC2135072/ /pubmed/19870959 Text en Copyright © Copyright, 1940, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Landsteiner, K.
Chase, M. W.
STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS : VII. SKIN SENSITIZATION BY INTRAPERITONEAL INJECTIONS
title STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS : VII. SKIN SENSITIZATION BY INTRAPERITONEAL INJECTIONS
title_full STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS : VII. SKIN SENSITIZATION BY INTRAPERITONEAL INJECTIONS
title_fullStr STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS : VII. SKIN SENSITIZATION BY INTRAPERITONEAL INJECTIONS
title_full_unstemmed STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS : VII. SKIN SENSITIZATION BY INTRAPERITONEAL INJECTIONS
title_short STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS : VII. SKIN SENSITIZATION BY INTRAPERITONEAL INJECTIONS
title_sort studies on the sensitization of animals with simple chemical compounds : vii. skin sensitization by intraperitoneal injections
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135072/
https://www.ncbi.nlm.nih.gov/pubmed/19870959
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