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STUDIES ON EXPERIMENTAL HYPERTENSION : XI. THE EFFECT OF EXCISION OF THE CAROTID SINUSES ON EXPERIMENTAL HYPERTENSION PRODUCED BY RENAL ISCHEMIA
Excision of both carotid sinuses, with or without section of cardio-aortic inhibitor fibers, was not followed by a significant change of femoral mean blood pressure from the normal. This procedure did not interfere with the development of hypertension produced by renal ischemia. There was no signifi...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1940
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135079/ https://www.ncbi.nlm.nih.gov/pubmed/19870955 |
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author | Goldblatt, Harry Kahn, Joseph R. Bayless, Francis Simon, Morris A. |
author_facet | Goldblatt, Harry Kahn, Joseph R. Bayless, Francis Simon, Morris A. |
author_sort | Goldblatt, Harry |
collection | PubMed |
description | Excision of both carotid sinuses, with or without section of cardio-aortic inhibitor fibers, was not followed by a significant change of femoral mean blood pressure from the normal. This procedure did not interfere with the development of hypertension produced by renal ischemia. There was no significant difference between the levels of hypertension due to renal ischemia in animals with both carotid sinuses previously excised and in those with both carotid sinuses intact. In one of three animals with hypertension due to renal ischemia, in which the elevated blood pressure had gradually subsided, there was a slight and only temporary reelevation of pressure after excision of both carotid sinuses. In the other two animals, excision of the carotid sinuses had no effect on the blood pressure. In all three, however, increased constriction of the renal arteries caused significant and persistent reelevation of the blood pressure. The carotid sinus has no demonstrable influence upon hypertension caused by renal ischemia, although in such animals it probably plays the same part in the regulation of blood pressure as it does in normal animals (7). |
format | Text |
id | pubmed-2135079 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1940 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21350792008-04-18 STUDIES ON EXPERIMENTAL HYPERTENSION : XI. THE EFFECT OF EXCISION OF THE CAROTID SINUSES ON EXPERIMENTAL HYPERTENSION PRODUCED BY RENAL ISCHEMIA Goldblatt, Harry Kahn, Joseph R. Bayless, Francis Simon, Morris A. J Exp Med Article Excision of both carotid sinuses, with or without section of cardio-aortic inhibitor fibers, was not followed by a significant change of femoral mean blood pressure from the normal. This procedure did not interfere with the development of hypertension produced by renal ischemia. There was no significant difference between the levels of hypertension due to renal ischemia in animals with both carotid sinuses previously excised and in those with both carotid sinuses intact. In one of three animals with hypertension due to renal ischemia, in which the elevated blood pressure had gradually subsided, there was a slight and only temporary reelevation of pressure after excision of both carotid sinuses. In the other two animals, excision of the carotid sinuses had no effect on the blood pressure. In all three, however, increased constriction of the renal arteries caused significant and persistent reelevation of the blood pressure. The carotid sinus has no demonstrable influence upon hypertension caused by renal ischemia, although in such animals it probably plays the same part in the regulation of blood pressure as it does in normal animals (7). The Rockefeller University Press 1940-01-31 /pmc/articles/PMC2135079/ /pubmed/19870955 Text en Copyright © Copyright, 1940, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Goldblatt, Harry Kahn, Joseph R. Bayless, Francis Simon, Morris A. STUDIES ON EXPERIMENTAL HYPERTENSION : XI. THE EFFECT OF EXCISION OF THE CAROTID SINUSES ON EXPERIMENTAL HYPERTENSION PRODUCED BY RENAL ISCHEMIA |
title | STUDIES ON EXPERIMENTAL HYPERTENSION : XI. THE EFFECT OF EXCISION OF THE CAROTID SINUSES ON EXPERIMENTAL HYPERTENSION PRODUCED BY RENAL ISCHEMIA |
title_full | STUDIES ON EXPERIMENTAL HYPERTENSION : XI. THE EFFECT OF EXCISION OF THE CAROTID SINUSES ON EXPERIMENTAL HYPERTENSION PRODUCED BY RENAL ISCHEMIA |
title_fullStr | STUDIES ON EXPERIMENTAL HYPERTENSION : XI. THE EFFECT OF EXCISION OF THE CAROTID SINUSES ON EXPERIMENTAL HYPERTENSION PRODUCED BY RENAL ISCHEMIA |
title_full_unstemmed | STUDIES ON EXPERIMENTAL HYPERTENSION : XI. THE EFFECT OF EXCISION OF THE CAROTID SINUSES ON EXPERIMENTAL HYPERTENSION PRODUCED BY RENAL ISCHEMIA |
title_short | STUDIES ON EXPERIMENTAL HYPERTENSION : XI. THE EFFECT OF EXCISION OF THE CAROTID SINUSES ON EXPERIMENTAL HYPERTENSION PRODUCED BY RENAL ISCHEMIA |
title_sort | studies on experimental hypertension : xi. the effect of excision of the carotid sinuses on experimental hypertension produced by renal ischemia |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135079/ https://www.ncbi.nlm.nih.gov/pubmed/19870955 |
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