THE BEHAVIOR OF POX VIRUSES IN THE RESPIRATORY TRACT : III. THE SURVIVAL OF VARIOLA AND VACCINIA VIRUSES IN THE LUNGS OF MICE PREVIOUSLY INFECTED WITH VARIOLA

Recovery from the transient pulmonary reaction which accompanies the nasal instillation of variola virus in mice was followed by a measurable protection against the homologous virus and also against vaccinia. Variola virus which regularly survived in the lung of normally susceptible mice through the...

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Detalles Bibliográficos
Autor principal: Nelson, John B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1940
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135094/
https://www.ncbi.nlm.nih.gov/pubmed/19870989
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author Nelson, John B.
author_facet Nelson, John B.
author_sort Nelson, John B.
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description Recovery from the transient pulmonary reaction which accompanies the nasal instillation of variola virus in mice was followed by a measurable protection against the homologous virus and also against vaccinia. Variola virus which regularly survived in the lung of normally susceptible mice through the 5th day was noticeably reduced in titer on the 3rd day in the lung of recovered animals, and usually eliminated by the 5th day. Vaccinia virus produced a less severe systemic reaction in recovered mice and its titer in the lung was significantly reduced on the 5th day. The residence of both viruses in the lung of recovered mice was attended by pathological changes, visible macroscopically.
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spelling pubmed-21350942008-04-18 THE BEHAVIOR OF POX VIRUSES IN THE RESPIRATORY TRACT : III. THE SURVIVAL OF VARIOLA AND VACCINIA VIRUSES IN THE LUNGS OF MICE PREVIOUSLY INFECTED WITH VARIOLA Nelson, John B. J Exp Med Article Recovery from the transient pulmonary reaction which accompanies the nasal instillation of variola virus in mice was followed by a measurable protection against the homologous virus and also against vaccinia. Variola virus which regularly survived in the lung of normally susceptible mice through the 5th day was noticeably reduced in titer on the 3rd day in the lung of recovered animals, and usually eliminated by the 5th day. Vaccinia virus produced a less severe systemic reaction in recovered mice and its titer in the lung was significantly reduced on the 5th day. The residence of both viruses in the lung of recovered mice was attended by pathological changes, visible macroscopically. The Rockefeller University Press 1940-04-30 /pmc/articles/PMC2135094/ /pubmed/19870989 Text en Copyright © Copyright, 1940, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Nelson, John B.
THE BEHAVIOR OF POX VIRUSES IN THE RESPIRATORY TRACT : III. THE SURVIVAL OF VARIOLA AND VACCINIA VIRUSES IN THE LUNGS OF MICE PREVIOUSLY INFECTED WITH VARIOLA
title THE BEHAVIOR OF POX VIRUSES IN THE RESPIRATORY TRACT : III. THE SURVIVAL OF VARIOLA AND VACCINIA VIRUSES IN THE LUNGS OF MICE PREVIOUSLY INFECTED WITH VARIOLA
title_full THE BEHAVIOR OF POX VIRUSES IN THE RESPIRATORY TRACT : III. THE SURVIVAL OF VARIOLA AND VACCINIA VIRUSES IN THE LUNGS OF MICE PREVIOUSLY INFECTED WITH VARIOLA
title_fullStr THE BEHAVIOR OF POX VIRUSES IN THE RESPIRATORY TRACT : III. THE SURVIVAL OF VARIOLA AND VACCINIA VIRUSES IN THE LUNGS OF MICE PREVIOUSLY INFECTED WITH VARIOLA
title_full_unstemmed THE BEHAVIOR OF POX VIRUSES IN THE RESPIRATORY TRACT : III. THE SURVIVAL OF VARIOLA AND VACCINIA VIRUSES IN THE LUNGS OF MICE PREVIOUSLY INFECTED WITH VARIOLA
title_short THE BEHAVIOR OF POX VIRUSES IN THE RESPIRATORY TRACT : III. THE SURVIVAL OF VARIOLA AND VACCINIA VIRUSES IN THE LUNGS OF MICE PREVIOUSLY INFECTED WITH VARIOLA
title_sort behavior of pox viruses in the respiratory tract : iii. the survival of variola and vaccinia viruses in the lungs of mice previously infected with variola
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135094/
https://www.ncbi.nlm.nih.gov/pubmed/19870989
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