III. METHOD FOR DETECTING POLIOMYELITIC VIRUS IN SEWAGE AND STOOLS

1. The active agent in sewage and aqueous suspensions of human stools, capable of producing poliomyelitis in rhesus monkeys after intraperitoneal inoculation, can be precipitated by 50 per cent saturation with ammonium sulfate, and no loss of activity seems to occur during this procedure. 2. The pre...

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Detalles Bibliográficos
Autor principal: Card, Sven
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1940
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135108/
https://www.ncbi.nlm.nih.gov/pubmed/19870998
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author Card, Sven
author_facet Card, Sven
author_sort Card, Sven
collection PubMed
description 1. The active agent in sewage and aqueous suspensions of human stools, capable of producing poliomyelitis in rhesus monkeys after intraperitoneal inoculation, can be precipitated by 50 per cent saturation with ammonium sulfate, and no loss of activity seems to occur during this procedure. 2. The precipitated virus is not consistently "redissolvable" in water. 3. By precipitation and subsequent dialysis of the precipitate, a preparation is obtained which may be smaller in volume, and is less toxic for monkeys, than was the original material. 4. The procedure can be applied in tests on the infectivity of stools, and sewage specimens.
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spelling pubmed-21351082008-04-18 III. METHOD FOR DETECTING POLIOMYELITIC VIRUS IN SEWAGE AND STOOLS Card, Sven J Exp Med Article 1. The active agent in sewage and aqueous suspensions of human stools, capable of producing poliomyelitis in rhesus monkeys after intraperitoneal inoculation, can be precipitated by 50 per cent saturation with ammonium sulfate, and no loss of activity seems to occur during this procedure. 2. The precipitated virus is not consistently "redissolvable" in water. 3. By precipitation and subsequent dialysis of the precipitate, a preparation is obtained which may be smaller in volume, and is less toxic for monkeys, than was the original material. 4. The procedure can be applied in tests on the infectivity of stools, and sewage specimens. The Rockefeller University Press 1940-05-31 /pmc/articles/PMC2135108/ /pubmed/19870998 Text en Copyright © Copyright, 1940, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Card, Sven
III. METHOD FOR DETECTING POLIOMYELITIC VIRUS IN SEWAGE AND STOOLS
title III. METHOD FOR DETECTING POLIOMYELITIC VIRUS IN SEWAGE AND STOOLS
title_full III. METHOD FOR DETECTING POLIOMYELITIC VIRUS IN SEWAGE AND STOOLS
title_fullStr III. METHOD FOR DETECTING POLIOMYELITIC VIRUS IN SEWAGE AND STOOLS
title_full_unstemmed III. METHOD FOR DETECTING POLIOMYELITIC VIRUS IN SEWAGE AND STOOLS
title_short III. METHOD FOR DETECTING POLIOMYELITIC VIRUS IN SEWAGE AND STOOLS
title_sort iii. method for detecting poliomyelitic virus in sewage and stools
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135108/
https://www.ncbi.nlm.nih.gov/pubmed/19870998
work_keys_str_mv AT cardsven iiimethodfordetectingpoliomyeliticvirusinsewageandstools

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