THE RÔLE OF RENAL METABOLISM IN HYPERTENSION AND UREMIA

1. The chemical mediator of renal hypertension is rapidly destroyed by the metabolic activity of the normal kidney. The excretory function of the kidney plays little, if any, rôle in eliminating the mediator of hypertension. 2. If specific substances are responsible for the uremic syndrome, they are...

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Detalles Bibliográficos
Autores principales: Rodbard, S., Katz, L. N.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1941
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135135/
https://www.ncbi.nlm.nih.gov/pubmed/19871083
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author Rodbard, S.
Katz, L. N.
author_facet Rodbard, S.
Katz, L. N.
author_sort Rodbard, S.
collection PubMed
description 1. The chemical mediator of renal hypertension is rapidly destroyed by the metabolic activity of the normal kidney. The excretory function of the kidney plays little, if any, rôle in eliminating the mediator of hypertension. 2. If specific substances are responsible for the uremic syndrome, they are neither produced nor eliminated to any significant extent by the metabolic activity of the kidneys. The elimination of these postulated uremia-producing substances would have to be primarily dependent upon the excretory activities of the kidney. 3. No evidence was obtained to support the view that a unilateral ureterovenous fistula leads to "nephrotoxic" symptoms.
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spelling pubmed-21351352008-04-18 THE RÔLE OF RENAL METABOLISM IN HYPERTENSION AND UREMIA Rodbard, S. Katz, L. N. J Exp Med Article 1. The chemical mediator of renal hypertension is rapidly destroyed by the metabolic activity of the normal kidney. The excretory function of the kidney plays little, if any, rôle in eliminating the mediator of hypertension. 2. If specific substances are responsible for the uremic syndrome, they are neither produced nor eliminated to any significant extent by the metabolic activity of the kidneys. The elimination of these postulated uremia-producing substances would have to be primarily dependent upon the excretory activities of the kidney. 3. No evidence was obtained to support the view that a unilateral ureterovenous fistula leads to "nephrotoxic" symptoms. The Rockefeller University Press 1941-02-28 /pmc/articles/PMC2135135/ /pubmed/19871083 Text en Copyright © Copyright, 1941, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Rodbard, S.
Katz, L. N.
THE RÔLE OF RENAL METABOLISM IN HYPERTENSION AND UREMIA
title THE RÔLE OF RENAL METABOLISM IN HYPERTENSION AND UREMIA
title_full THE RÔLE OF RENAL METABOLISM IN HYPERTENSION AND UREMIA
title_fullStr THE RÔLE OF RENAL METABOLISM IN HYPERTENSION AND UREMIA
title_full_unstemmed THE RÔLE OF RENAL METABOLISM IN HYPERTENSION AND UREMIA
title_short THE RÔLE OF RENAL METABOLISM IN HYPERTENSION AND UREMIA
title_sort rôle of renal metabolism in hypertension and uremia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135135/
https://www.ncbi.nlm.nih.gov/pubmed/19871083
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