A VIRUS FROM CASES OF ATYPICAL PNEUMONIA : RELATION TO THE VIRUSES OF MENINGOPNEUMONITIS AND PSITTACOSIS

From the lungs of two fatal cases and from the sputum of two non-fatal cases of atypical bronchopneumonia, a psittacosis-like virus was isolated by direct intranasal inoculation of mice. Intraperitoneal injection of the same human material into mice gave negative results. The virus has a relatively...

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Detalles Bibliográficos
Autores principales: Eaton, Monroe D., Beck, M. Dorthy, Pearson, Harold E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1941
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135153/
https://www.ncbi.nlm.nih.gov/pubmed/19871102
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author Eaton, Monroe D.
Beck, M. Dorthy
Pearson, Harold E.
author_facet Eaton, Monroe D.
Beck, M. Dorthy
Pearson, Harold E.
author_sort Eaton, Monroe D.
collection PubMed
description From the lungs of two fatal cases and from the sputum of two non-fatal cases of atypical bronchopneumonia, a psittacosis-like virus was isolated by direct intranasal inoculation of mice. Intraperitoneal injection of the same human material into mice gave negative results. The virus has a relatively high virulence for mice by intranasal or intra-cerebral inoculation, but does not kill after intraperitoneal inoculation. Its virulence for Java ricebirds is low and it fails to produce a carrier state in mice and birds. Two cases showed an increase in complement-fixing antibodies to the new virus and to psittacosis. The virus is antigenically related to the viruses of meningopneumonitis and psittacosis by complement fixation and by active immunity tests in mice.
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spelling pubmed-21351532008-04-18 A VIRUS FROM CASES OF ATYPICAL PNEUMONIA : RELATION TO THE VIRUSES OF MENINGOPNEUMONITIS AND PSITTACOSIS Eaton, Monroe D. Beck, M. Dorthy Pearson, Harold E. J Exp Med Article From the lungs of two fatal cases and from the sputum of two non-fatal cases of atypical bronchopneumonia, a psittacosis-like virus was isolated by direct intranasal inoculation of mice. Intraperitoneal injection of the same human material into mice gave negative results. The virus has a relatively high virulence for mice by intranasal or intra-cerebral inoculation, but does not kill after intraperitoneal inoculation. Its virulence for Java ricebirds is low and it fails to produce a carrier state in mice and birds. Two cases showed an increase in complement-fixing antibodies to the new virus and to psittacosis. The virus is antigenically related to the viruses of meningopneumonitis and psittacosis by complement fixation and by active immunity tests in mice. The Rockefeller University Press 1941-04-30 /pmc/articles/PMC2135153/ /pubmed/19871102 Text en Copyright © Copyright, 1941, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Eaton, Monroe D.
Beck, M. Dorthy
Pearson, Harold E.
A VIRUS FROM CASES OF ATYPICAL PNEUMONIA : RELATION TO THE VIRUSES OF MENINGOPNEUMONITIS AND PSITTACOSIS
title A VIRUS FROM CASES OF ATYPICAL PNEUMONIA : RELATION TO THE VIRUSES OF MENINGOPNEUMONITIS AND PSITTACOSIS
title_full A VIRUS FROM CASES OF ATYPICAL PNEUMONIA : RELATION TO THE VIRUSES OF MENINGOPNEUMONITIS AND PSITTACOSIS
title_fullStr A VIRUS FROM CASES OF ATYPICAL PNEUMONIA : RELATION TO THE VIRUSES OF MENINGOPNEUMONITIS AND PSITTACOSIS
title_full_unstemmed A VIRUS FROM CASES OF ATYPICAL PNEUMONIA : RELATION TO THE VIRUSES OF MENINGOPNEUMONITIS AND PSITTACOSIS
title_short A VIRUS FROM CASES OF ATYPICAL PNEUMONIA : RELATION TO THE VIRUSES OF MENINGOPNEUMONITIS AND PSITTACOSIS
title_sort virus from cases of atypical pneumonia : relation to the viruses of meningopneumonitis and psittacosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135153/
https://www.ncbi.nlm.nih.gov/pubmed/19871102
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