LIVER DAMAGE AND URINARY EXCRETION OF SULFATE IN RATS FED l-CYSTINE, dl-METHIONINE, AND CYSTEIC ACID

1. Rats fed l-cystine at excessive levels excrete large amounts of sulfate sulfur in the urine and develop liver necrosis and cirrhosis. 2. Rats fed dl-methionine at excessive levels excrete large amounts of sulfate sulfur, but do not develop liver necrosis and cirrhosis. 3. Rats fed cysteic acid at...

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Detalles Bibliográficos
Autores principales: Earle, David P., Kendall, Forrest E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1942
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135241/
https://www.ncbi.nlm.nih.gov/pubmed/19871176
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author Earle, David P.
Kendall, Forrest E.
author_facet Earle, David P.
Kendall, Forrest E.
author_sort Earle, David P.
collection PubMed
description 1. Rats fed l-cystine at excessive levels excrete large amounts of sulfate sulfur in the urine and develop liver necrosis and cirrhosis. 2. Rats fed dl-methionine at excessive levels excrete large amounts of sulfate sulfur, but do not develop liver necrosis and cirrhosis. 3. Rats fed cysteic acid at high levels excrete relatively small amounts of sulfate, but do develop liver necrosis and cirrhosis. 4. In conclusion, there is no apparent correlation between the amount of sulfate formed and the development of liver damage in rats fed l-cystine, dl-methionine, and cysteic acids.
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spelling pubmed-21352412008-04-18 LIVER DAMAGE AND URINARY EXCRETION OF SULFATE IN RATS FED l-CYSTINE, dl-METHIONINE, AND CYSTEIC ACID Earle, David P. Kendall, Forrest E. J Exp Med Article 1. Rats fed l-cystine at excessive levels excrete large amounts of sulfate sulfur in the urine and develop liver necrosis and cirrhosis. 2. Rats fed dl-methionine at excessive levels excrete large amounts of sulfate sulfur, but do not develop liver necrosis and cirrhosis. 3. Rats fed cysteic acid at high levels excrete relatively small amounts of sulfate, but do develop liver necrosis and cirrhosis. 4. In conclusion, there is no apparent correlation between the amount of sulfate formed and the development of liver damage in rats fed l-cystine, dl-methionine, and cysteic acids. The Rockefeller University Press 1942-01-31 /pmc/articles/PMC2135241/ /pubmed/19871176 Text en Copyright © Copyright, 1942, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Earle, David P.
Kendall, Forrest E.
LIVER DAMAGE AND URINARY EXCRETION OF SULFATE IN RATS FED l-CYSTINE, dl-METHIONINE, AND CYSTEIC ACID
title LIVER DAMAGE AND URINARY EXCRETION OF SULFATE IN RATS FED l-CYSTINE, dl-METHIONINE, AND CYSTEIC ACID
title_full LIVER DAMAGE AND URINARY EXCRETION OF SULFATE IN RATS FED l-CYSTINE, dl-METHIONINE, AND CYSTEIC ACID
title_fullStr LIVER DAMAGE AND URINARY EXCRETION OF SULFATE IN RATS FED l-CYSTINE, dl-METHIONINE, AND CYSTEIC ACID
title_full_unstemmed LIVER DAMAGE AND URINARY EXCRETION OF SULFATE IN RATS FED l-CYSTINE, dl-METHIONINE, AND CYSTEIC ACID
title_short LIVER DAMAGE AND URINARY EXCRETION OF SULFATE IN RATS FED l-CYSTINE, dl-METHIONINE, AND CYSTEIC ACID
title_sort liver damage and urinary excretion of sulfate in rats fed l-cystine, dl-methionine, and cysteic acid
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135241/
https://www.ncbi.nlm.nih.gov/pubmed/19871176
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