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HUMAN ALLERGY TO MAMMALIAN SERA

Four patients allergic to many mammalian sera were found to have circulating, skin-sensitizing antibodies for these sera. A study of these antibodies by in vitro neutralization and subsequent local passive transfer showed that, in the case of each patient, one particular mammalian serum neutralized...

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Detalles Bibliográficos
Autor principal: Simon, Frank A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1942
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135245/
https://www.ncbi.nlm.nih.gov/pubmed/19871186
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author Simon, Frank A.
author_facet Simon, Frank A.
author_sort Simon, Frank A.
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description Four patients allergic to many mammalian sera were found to have circulating, skin-sensitizing antibodies for these sera. A study of these antibodies by in vitro neutralization and subsequent local passive transfer showed that, in the case of each patient, one particular mammalian serum neutralized antibodies for all sera whereas other mammalian sera neutralized antibodies for themselves alone or for themselves plus one or several additional sera but not for all sera. The possibility of multiple common allergenic determinants in mammalian sera is discussed.
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spelling pubmed-21352452008-04-18 HUMAN ALLERGY TO MAMMALIAN SERA Simon, Frank A. J Exp Med Article Four patients allergic to many mammalian sera were found to have circulating, skin-sensitizing antibodies for these sera. A study of these antibodies by in vitro neutralization and subsequent local passive transfer showed that, in the case of each patient, one particular mammalian serum neutralized antibodies for all sera whereas other mammalian sera neutralized antibodies for themselves alone or for themselves plus one or several additional sera but not for all sera. The possibility of multiple common allergenic determinants in mammalian sera is discussed. The Rockefeller University Press 1942-03-01 /pmc/articles/PMC2135245/ /pubmed/19871186 Text en Copyright © Copyright, 1942, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Simon, Frank A.
HUMAN ALLERGY TO MAMMALIAN SERA
title HUMAN ALLERGY TO MAMMALIAN SERA
title_full HUMAN ALLERGY TO MAMMALIAN SERA
title_fullStr HUMAN ALLERGY TO MAMMALIAN SERA
title_full_unstemmed HUMAN ALLERGY TO MAMMALIAN SERA
title_short HUMAN ALLERGY TO MAMMALIAN SERA
title_sort human allergy to mammalian sera
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135245/
https://www.ncbi.nlm.nih.gov/pubmed/19871186
work_keys_str_mv AT simonfranka humanallergytomammaliansera