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STUDIES ON HYPOALBUMINEMIA PRODUCED BY PROTEIN-DEFICIENT DIETS : III. THE CORRECTION OF HYPOALBUMINEMIA IN DOGS BY MEANS OF LARGE PLASMA TRANSFUSIONS
1. It proved possible to correct dietary hypoalbuminemia in dogs by large plasma transfusions (about 50 cc. per kilo per day). After 1 week of injections the increase of plasma protein exceeded the normal level although but 10 to 13 per cent of the injected protein remained in the blood. There was a...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1943
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135293/ https://www.ncbi.nlm.nih.gov/pubmed/19871260 |
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author | Elman, Robert Davey, Harriet Wolf |
author_facet | Elman, Robert Davey, Harriet Wolf |
author_sort | Elman, Robert |
collection | PubMed |
description | 1. It proved possible to correct dietary hypoalbuminemia in dogs by large plasma transfusions (about 50 cc. per kilo per day). After 1 week of injections the increase of plasma protein exceeded the normal level although but 10 to 13 per cent of the injected protein remained in the blood. There was an associated increase in plasma volume and a marked diuresis. During the following 2 weeks the plasma volume and protein returned to their previous low levels. 2. The nitrogen introduced was retained and produced no change in urinary excretion during the week of plasma injections, but in the following 2 weeks there was an increased nitrogen output. The inference would seem to be that the large amounts of plasma injected in these experiments were not permanently utilized by the body as nitrogenous nourishment but after some delay were largely excreted in the urine. |
format | Text |
id | pubmed-2135293 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1943 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21352932008-04-18 STUDIES ON HYPOALBUMINEMIA PRODUCED BY PROTEIN-DEFICIENT DIETS : III. THE CORRECTION OF HYPOALBUMINEMIA IN DOGS BY MEANS OF LARGE PLASMA TRANSFUSIONS Elman, Robert Davey, Harriet Wolf J Exp Med Article 1. It proved possible to correct dietary hypoalbuminemia in dogs by large plasma transfusions (about 50 cc. per kilo per day). After 1 week of injections the increase of plasma protein exceeded the normal level although but 10 to 13 per cent of the injected protein remained in the blood. There was an associated increase in plasma volume and a marked diuresis. During the following 2 weeks the plasma volume and protein returned to their previous low levels. 2. The nitrogen introduced was retained and produced no change in urinary excretion during the week of plasma injections, but in the following 2 weeks there was an increased nitrogen output. The inference would seem to be that the large amounts of plasma injected in these experiments were not permanently utilized by the body as nitrogenous nourishment but after some delay were largely excreted in the urine. The Rockefeller University Press 1943-01-01 /pmc/articles/PMC2135293/ /pubmed/19871260 Text en Copyright © Copyright, 1943, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Elman, Robert Davey, Harriet Wolf STUDIES ON HYPOALBUMINEMIA PRODUCED BY PROTEIN-DEFICIENT DIETS : III. THE CORRECTION OF HYPOALBUMINEMIA IN DOGS BY MEANS OF LARGE PLASMA TRANSFUSIONS |
title | STUDIES ON HYPOALBUMINEMIA PRODUCED BY PROTEIN-DEFICIENT DIETS : III. THE CORRECTION OF HYPOALBUMINEMIA IN DOGS BY MEANS OF LARGE PLASMA TRANSFUSIONS |
title_full | STUDIES ON HYPOALBUMINEMIA PRODUCED BY PROTEIN-DEFICIENT DIETS : III. THE CORRECTION OF HYPOALBUMINEMIA IN DOGS BY MEANS OF LARGE PLASMA TRANSFUSIONS |
title_fullStr | STUDIES ON HYPOALBUMINEMIA PRODUCED BY PROTEIN-DEFICIENT DIETS : III. THE CORRECTION OF HYPOALBUMINEMIA IN DOGS BY MEANS OF LARGE PLASMA TRANSFUSIONS |
title_full_unstemmed | STUDIES ON HYPOALBUMINEMIA PRODUCED BY PROTEIN-DEFICIENT DIETS : III. THE CORRECTION OF HYPOALBUMINEMIA IN DOGS BY MEANS OF LARGE PLASMA TRANSFUSIONS |
title_short | STUDIES ON HYPOALBUMINEMIA PRODUCED BY PROTEIN-DEFICIENT DIETS : III. THE CORRECTION OF HYPOALBUMINEMIA IN DOGS BY MEANS OF LARGE PLASMA TRANSFUSIONS |
title_sort | studies on hypoalbuminemia produced by protein-deficient diets : iii. the correction of hypoalbuminemia in dogs by means of large plasma transfusions |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135293/ https://www.ncbi.nlm.nih.gov/pubmed/19871260 |
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