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STUDIES ON HYPOALBUMINEMIA PRODUCED BY PROTEIN-DEFICIENT DIETS : III. THE CORRECTION OF HYPOALBUMINEMIA IN DOGS BY MEANS OF LARGE PLASMA TRANSFUSIONS

1. It proved possible to correct dietary hypoalbuminemia in dogs by large plasma transfusions (about 50 cc. per kilo per day). After 1 week of injections the increase of plasma protein exceeded the normal level although but 10 to 13 per cent of the injected protein remained in the blood. There was a...

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Detalles Bibliográficos
Autores principales: Elman, Robert, Davey, Harriet Wolf
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1943
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135293/
https://www.ncbi.nlm.nih.gov/pubmed/19871260
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author Elman, Robert
Davey, Harriet Wolf
author_facet Elman, Robert
Davey, Harriet Wolf
author_sort Elman, Robert
collection PubMed
description 1. It proved possible to correct dietary hypoalbuminemia in dogs by large plasma transfusions (about 50 cc. per kilo per day). After 1 week of injections the increase of plasma protein exceeded the normal level although but 10 to 13 per cent of the injected protein remained in the blood. There was an associated increase in plasma volume and a marked diuresis. During the following 2 weeks the plasma volume and protein returned to their previous low levels. 2. The nitrogen introduced was retained and produced no change in urinary excretion during the week of plasma injections, but in the following 2 weeks there was an increased nitrogen output. The inference would seem to be that the large amounts of plasma injected in these experiments were not permanently utilized by the body as nitrogenous nourishment but after some delay were largely excreted in the urine.
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spelling pubmed-21352932008-04-18 STUDIES ON HYPOALBUMINEMIA PRODUCED BY PROTEIN-DEFICIENT DIETS : III. THE CORRECTION OF HYPOALBUMINEMIA IN DOGS BY MEANS OF LARGE PLASMA TRANSFUSIONS Elman, Robert Davey, Harriet Wolf J Exp Med Article 1. It proved possible to correct dietary hypoalbuminemia in dogs by large plasma transfusions (about 50 cc. per kilo per day). After 1 week of injections the increase of plasma protein exceeded the normal level although but 10 to 13 per cent of the injected protein remained in the blood. There was an associated increase in plasma volume and a marked diuresis. During the following 2 weeks the plasma volume and protein returned to their previous low levels. 2. The nitrogen introduced was retained and produced no change in urinary excretion during the week of plasma injections, but in the following 2 weeks there was an increased nitrogen output. The inference would seem to be that the large amounts of plasma injected in these experiments were not permanently utilized by the body as nitrogenous nourishment but after some delay were largely excreted in the urine. The Rockefeller University Press 1943-01-01 /pmc/articles/PMC2135293/ /pubmed/19871260 Text en Copyright © Copyright, 1943, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Elman, Robert
Davey, Harriet Wolf
STUDIES ON HYPOALBUMINEMIA PRODUCED BY PROTEIN-DEFICIENT DIETS : III. THE CORRECTION OF HYPOALBUMINEMIA IN DOGS BY MEANS OF LARGE PLASMA TRANSFUSIONS
title STUDIES ON HYPOALBUMINEMIA PRODUCED BY PROTEIN-DEFICIENT DIETS : III. THE CORRECTION OF HYPOALBUMINEMIA IN DOGS BY MEANS OF LARGE PLASMA TRANSFUSIONS
title_full STUDIES ON HYPOALBUMINEMIA PRODUCED BY PROTEIN-DEFICIENT DIETS : III. THE CORRECTION OF HYPOALBUMINEMIA IN DOGS BY MEANS OF LARGE PLASMA TRANSFUSIONS
title_fullStr STUDIES ON HYPOALBUMINEMIA PRODUCED BY PROTEIN-DEFICIENT DIETS : III. THE CORRECTION OF HYPOALBUMINEMIA IN DOGS BY MEANS OF LARGE PLASMA TRANSFUSIONS
title_full_unstemmed STUDIES ON HYPOALBUMINEMIA PRODUCED BY PROTEIN-DEFICIENT DIETS : III. THE CORRECTION OF HYPOALBUMINEMIA IN DOGS BY MEANS OF LARGE PLASMA TRANSFUSIONS
title_short STUDIES ON HYPOALBUMINEMIA PRODUCED BY PROTEIN-DEFICIENT DIETS : III. THE CORRECTION OF HYPOALBUMINEMIA IN DOGS BY MEANS OF LARGE PLASMA TRANSFUSIONS
title_sort studies on hypoalbuminemia produced by protein-deficient diets : iii. the correction of hypoalbuminemia in dogs by means of large plasma transfusions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135293/
https://www.ncbi.nlm.nih.gov/pubmed/19871260
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