FUNCTION OF COMPONENTS OF COMPLEMENT IN IMMUNE HEMOLYSIS

1. At a temperature of 1°C., C'2, C'4, and C'1 combine with sensitized sheep erythrocytes, while C'3 does not combine. 2. C'1, although combining with sensitized cells in the absence of C'4, is hemolytically inert unless C'4 combines previous to, or simultaneously...

Descripción completa

Detalles Bibliográficos
Autores principales: Pillemer, L., Seifter, S., Chu, Fey, Ecker, E. E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1942
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135297/
https://www.ncbi.nlm.nih.gov/pubmed/19871223
_version_ 1782142863602089984
author Pillemer, L.
Seifter, S.
Chu, Fey
Ecker, E. E.
author_facet Pillemer, L.
Seifter, S.
Chu, Fey
Ecker, E. E.
author_sort Pillemer, L.
collection PubMed
description 1. At a temperature of 1°C., C'2, C'4, and C'1 combine with sensitized sheep erythrocytes, while C'3 does not combine. 2. C'1, although combining with sensitized cells in the absence of C'4, is hemolytically inert unless C'4 combines previous to, or simultaneously with it. 3. C'4 does not combine in the absence of C'1. 4. Although C'3 is not fixed by antibody-sheep cell aggregates, it is essential for hemolysis, operating on the sensitized red cell after the fixation of C'4, C'2, and C'1 and behaving as if it were a catalyst.
format Text
id pubmed-2135297
institution National Center for Biotechnology Information
language English
publishDate 1942
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21352972008-04-18 FUNCTION OF COMPONENTS OF COMPLEMENT IN IMMUNE HEMOLYSIS Pillemer, L. Seifter, S. Chu, Fey Ecker, E. E. J Exp Med Article 1. At a temperature of 1°C., C'2, C'4, and C'1 combine with sensitized sheep erythrocytes, while C'3 does not combine. 2. C'1, although combining with sensitized cells in the absence of C'4, is hemolytically inert unless C'4 combines previous to, or simultaneously with it. 3. C'4 does not combine in the absence of C'1. 4. Although C'3 is not fixed by antibody-sheep cell aggregates, it is essential for hemolysis, operating on the sensitized red cell after the fixation of C'4, C'2, and C'1 and behaving as if it were a catalyst. The Rockefeller University Press 1942-07-01 /pmc/articles/PMC2135297/ /pubmed/19871223 Text en Copyright © Copyright, 1942, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Pillemer, L.
Seifter, S.
Chu, Fey
Ecker, E. E.
FUNCTION OF COMPONENTS OF COMPLEMENT IN IMMUNE HEMOLYSIS
title FUNCTION OF COMPONENTS OF COMPLEMENT IN IMMUNE HEMOLYSIS
title_full FUNCTION OF COMPONENTS OF COMPLEMENT IN IMMUNE HEMOLYSIS
title_fullStr FUNCTION OF COMPONENTS OF COMPLEMENT IN IMMUNE HEMOLYSIS
title_full_unstemmed FUNCTION OF COMPONENTS OF COMPLEMENT IN IMMUNE HEMOLYSIS
title_short FUNCTION OF COMPONENTS OF COMPLEMENT IN IMMUNE HEMOLYSIS
title_sort function of components of complement in immune hemolysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135297/
https://www.ncbi.nlm.nih.gov/pubmed/19871223
work_keys_str_mv AT pillemerl functionofcomponentsofcomplementinimmunehemolysis
AT seifters functionofcomponentsofcomplementinimmunehemolysis
AT chufey functionofcomponentsofcomplementinimmunehemolysis
AT eckeree functionofcomponentsofcomplementinimmunehemolysis

Ejemplares similares