Cargando…

ALLERGENIC RELATIONSHIP OF THE POLLENS OF DWARF AND GIANT RAGWEED TO SEVERAL OF THEIR BOTANIC RELATIVES

Thirty-eight of forty patients, allergic to the pollen of dwarf and giant ragweed, were found to be allergic also to the pollen of botanically related species. There was definite variation in the degree of reactivity to the various pollens in different patients. One additional patient reacted to dwa...

Descripción completa

Detalles Bibliográficos
Autor principal: Simon, Frank A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1943
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135324/
https://www.ncbi.nlm.nih.gov/pubmed/19871274
_version_ 1782142869870477312
author Simon, Frank A.
author_facet Simon, Frank A.
author_sort Simon, Frank A.
collection PubMed
description Thirty-eight of forty patients, allergic to the pollen of dwarf and giant ragweed, were found to be allergic also to the pollen of botanically related species. There was definite variation in the degree of reactivity to the various pollens in different patients. One additional patient reacted to dwarf ragweed but not to giant ragweed or to four other composites. Antibody neutralization studies in six cases indicated that (a) in four cases dwarf ragweed could have been the only sensitizing allergen. (b) In one case either dwarf or giant ragweed could have been the only sensitizing allergen. (c) In one case cosmos plus either of the ragweeds or some undetermined pollen could have been the sensitizing allergen, (d) In none of the six cases studied could cosmos, sunflower, goldenrod, or dandelion have been the only sensitizing allergens. The evidence presented supports the following concepts: (1) Hypersensitiveness of this type develops as the result of allergenic stimulation. (2) The pollens of the ragweeds and their botanic relatives contain, in addition to species-specific allergens, multiple common allergenic determinants which vary in their distribution among related species. (3) A person exposed simultaneously to a group of allergens may become sensitized to certain members of the group and not to others, while another person, exposed to the same group of allergens, may become sensitized to different members of the group.
format Text
id pubmed-2135324
institution National Center for Biotechnology Information
language English
publishDate 1943
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21353242008-04-18 ALLERGENIC RELATIONSHIP OF THE POLLENS OF DWARF AND GIANT RAGWEED TO SEVERAL OF THEIR BOTANIC RELATIVES Simon, Frank A. J Exp Med Article Thirty-eight of forty patients, allergic to the pollen of dwarf and giant ragweed, were found to be allergic also to the pollen of botanically related species. There was definite variation in the degree of reactivity to the various pollens in different patients. One additional patient reacted to dwarf ragweed but not to giant ragweed or to four other composites. Antibody neutralization studies in six cases indicated that (a) in four cases dwarf ragweed could have been the only sensitizing allergen. (b) In one case either dwarf or giant ragweed could have been the only sensitizing allergen. (c) In one case cosmos plus either of the ragweeds or some undetermined pollen could have been the sensitizing allergen, (d) In none of the six cases studied could cosmos, sunflower, goldenrod, or dandelion have been the only sensitizing allergens. The evidence presented supports the following concepts: (1) Hypersensitiveness of this type develops as the result of allergenic stimulation. (2) The pollens of the ragweeds and their botanic relatives contain, in addition to species-specific allergens, multiple common allergenic determinants which vary in their distribution among related species. (3) A person exposed simultaneously to a group of allergens may become sensitized to certain members of the group and not to others, while another person, exposed to the same group of allergens, may become sensitized to different members of the group. The Rockefeller University Press 1943-02-01 /pmc/articles/PMC2135324/ /pubmed/19871274 Text en Copyright © Copyright, 1943, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Simon, Frank A.
ALLERGENIC RELATIONSHIP OF THE POLLENS OF DWARF AND GIANT RAGWEED TO SEVERAL OF THEIR BOTANIC RELATIVES
title ALLERGENIC RELATIONSHIP OF THE POLLENS OF DWARF AND GIANT RAGWEED TO SEVERAL OF THEIR BOTANIC RELATIVES
title_full ALLERGENIC RELATIONSHIP OF THE POLLENS OF DWARF AND GIANT RAGWEED TO SEVERAL OF THEIR BOTANIC RELATIVES
title_fullStr ALLERGENIC RELATIONSHIP OF THE POLLENS OF DWARF AND GIANT RAGWEED TO SEVERAL OF THEIR BOTANIC RELATIVES
title_full_unstemmed ALLERGENIC RELATIONSHIP OF THE POLLENS OF DWARF AND GIANT RAGWEED TO SEVERAL OF THEIR BOTANIC RELATIVES
title_short ALLERGENIC RELATIONSHIP OF THE POLLENS OF DWARF AND GIANT RAGWEED TO SEVERAL OF THEIR BOTANIC RELATIVES
title_sort allergenic relationship of the pollens of dwarf and giant ragweed to several of their botanic relatives
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135324/
https://www.ncbi.nlm.nih.gov/pubmed/19871274
work_keys_str_mv AT simonfranka allergenicrelationshipofthepollensofdwarfandgiantragweedtoseveraloftheirbotanicrelatives