THE MULTIPLICATION OF BACTERIOPHAGE IN VIVO AND ITS PROTECTIVE EFFECT AGAINST AN EXPERIMENTAL INFECTION WITH SHIGELLA DYSENTERIAE

1. Anti-Shiga bacteriophage injected into the general circulation can multiply in the brain of mice infected intracerebrally with Shigella dysenteriae. 2. Under proper conditions, the injection of active bacteriophage into the general circulation can protect mice against an otherwise fatal intracere...

Descripción completa

Detalles Bibliográficos
Autores principales: Dubos, René J., Straus, June Hookey, Pierce, Cynthia
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1943
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135327/
https://www.ncbi.nlm.nih.gov/pubmed/19871319
_version_ 1782142870551003136
author Dubos, René J.
Straus, June Hookey
Pierce, Cynthia
author_facet Dubos, René J.
Straus, June Hookey
Pierce, Cynthia
author_sort Dubos, René J.
collection PubMed
description 1. Anti-Shiga bacteriophage injected into the general circulation can multiply in the brain of mice infected intracerebrally with Shigella dysenteriae. 2. Under proper conditions, the injection of active bacteriophage into the general circulation can protect mice against an otherwise fatal intracerebral infection with Shigella dysenteriae. 3. The protection so induced appears to depend upon the early establishment of a high bacteriophage level in the infected animal.
format Text
id pubmed-2135327
institution National Center for Biotechnology Information
language English
publishDate 1943
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21353272008-04-18 THE MULTIPLICATION OF BACTERIOPHAGE IN VIVO AND ITS PROTECTIVE EFFECT AGAINST AN EXPERIMENTAL INFECTION WITH SHIGELLA DYSENTERIAE Dubos, René J. Straus, June Hookey Pierce, Cynthia J Exp Med Article 1. Anti-Shiga bacteriophage injected into the general circulation can multiply in the brain of mice infected intracerebrally with Shigella dysenteriae. 2. Under proper conditions, the injection of active bacteriophage into the general circulation can protect mice against an otherwise fatal intracerebral infection with Shigella dysenteriae. 3. The protection so induced appears to depend upon the early establishment of a high bacteriophage level in the infected animal. The Rockefeller University Press 1943-09-01 /pmc/articles/PMC2135327/ /pubmed/19871319 Text en Copyright © Copyright, 1943, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Dubos, René J.
Straus, June Hookey
Pierce, Cynthia
THE MULTIPLICATION OF BACTERIOPHAGE IN VIVO AND ITS PROTECTIVE EFFECT AGAINST AN EXPERIMENTAL INFECTION WITH SHIGELLA DYSENTERIAE
title THE MULTIPLICATION OF BACTERIOPHAGE IN VIVO AND ITS PROTECTIVE EFFECT AGAINST AN EXPERIMENTAL INFECTION WITH SHIGELLA DYSENTERIAE
title_full THE MULTIPLICATION OF BACTERIOPHAGE IN VIVO AND ITS PROTECTIVE EFFECT AGAINST AN EXPERIMENTAL INFECTION WITH SHIGELLA DYSENTERIAE
title_fullStr THE MULTIPLICATION OF BACTERIOPHAGE IN VIVO AND ITS PROTECTIVE EFFECT AGAINST AN EXPERIMENTAL INFECTION WITH SHIGELLA DYSENTERIAE
title_full_unstemmed THE MULTIPLICATION OF BACTERIOPHAGE IN VIVO AND ITS PROTECTIVE EFFECT AGAINST AN EXPERIMENTAL INFECTION WITH SHIGELLA DYSENTERIAE
title_short THE MULTIPLICATION OF BACTERIOPHAGE IN VIVO AND ITS PROTECTIVE EFFECT AGAINST AN EXPERIMENTAL INFECTION WITH SHIGELLA DYSENTERIAE
title_sort multiplication of bacteriophage in vivo and its protective effect against an experimental infection with shigella dysenteriae
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135327/
https://www.ncbi.nlm.nih.gov/pubmed/19871319
work_keys_str_mv AT dubosrenej themultiplicationofbacteriophageinvivoanditsprotectiveeffectagainstanexperimentalinfectionwithshigelladysenteriae
AT strausjunehookey themultiplicationofbacteriophageinvivoanditsprotectiveeffectagainstanexperimentalinfectionwithshigelladysenteriae
AT piercecynthia themultiplicationofbacteriophageinvivoanditsprotectiveeffectagainstanexperimentalinfectionwithshigelladysenteriae
AT dubosrenej multiplicationofbacteriophageinvivoanditsprotectiveeffectagainstanexperimentalinfectionwithshigelladysenteriae
AT strausjunehookey multiplicationofbacteriophageinvivoanditsprotectiveeffectagainstanexperimentalinfectionwithshigelladysenteriae
AT piercecynthia multiplicationofbacteriophageinvivoanditsprotectiveeffectagainstanexperimentalinfectionwithshigelladysenteriae

Ejemplares similares