THE ELIMINATION OF ADMINISTERED ZINC IN PANCREATIC JUICE, DUODENAL JUICE, AND BILE OF THE DOG AS MEASURED BY ITS RADIOACTIVE ISOTOPE (Zn(65))

The excretion of intravenously injected labeled zinc into pancreatic juice, duodenal juice, and bile of the dog was investigated. The use of the radioactive isotope permitted the injection of minute amounts of zinc, amounts that were negligible when compared with the total amount of zinc already pre...

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Detalles Bibliográficos
Autores principales: Montgomery, M. Laurence, Sheline, G. E., Chaikoff, I. L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1943
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135328/
https://www.ncbi.nlm.nih.gov/pubmed/19871318
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author Montgomery, M. Laurence
Sheline, G. E.
Chaikoff, I. L.
author_facet Montgomery, M. Laurence
Sheline, G. E.
Chaikoff, I. L.
author_sort Montgomery, M. Laurence
collection PubMed
description The excretion of intravenously injected labeled zinc into pancreatic juice, duodenal juice, and bile of the dog was investigated. The use of the radioactive isotope permitted the injection of minute amounts of zinc, amounts that were negligible when compared with the total amount of zinc already present in the animal. 1. A large proportion of the injected Zn(65) was eliminated by way of the external secretion of the pancreas. As much as 11 per cent was excreted in the pancreatic juice in 14 days. 2. Very little of the administered radiozinc appeared in the bile. The maximum excretion observed for this pathway was 0.4 per cent in 8 days. 3. Radiozinc was also found in large amounts in the juice obtained from an isolated loop of the duodenum.
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spelling pubmed-21353282008-04-18 THE ELIMINATION OF ADMINISTERED ZINC IN PANCREATIC JUICE, DUODENAL JUICE, AND BILE OF THE DOG AS MEASURED BY ITS RADIOACTIVE ISOTOPE (Zn(65)) Montgomery, M. Laurence Sheline, G. E. Chaikoff, I. L. J Exp Med Article The excretion of intravenously injected labeled zinc into pancreatic juice, duodenal juice, and bile of the dog was investigated. The use of the radioactive isotope permitted the injection of minute amounts of zinc, amounts that were negligible when compared with the total amount of zinc already present in the animal. 1. A large proportion of the injected Zn(65) was eliminated by way of the external secretion of the pancreas. As much as 11 per cent was excreted in the pancreatic juice in 14 days. 2. Very little of the administered radiozinc appeared in the bile. The maximum excretion observed for this pathway was 0.4 per cent in 8 days. 3. Radiozinc was also found in large amounts in the juice obtained from an isolated loop of the duodenum. The Rockefeller University Press 1943-09-01 /pmc/articles/PMC2135328/ /pubmed/19871318 Text en Copyright © Copyright, 1943, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Montgomery, M. Laurence
Sheline, G. E.
Chaikoff, I. L.
THE ELIMINATION OF ADMINISTERED ZINC IN PANCREATIC JUICE, DUODENAL JUICE, AND BILE OF THE DOG AS MEASURED BY ITS RADIOACTIVE ISOTOPE (Zn(65))
title THE ELIMINATION OF ADMINISTERED ZINC IN PANCREATIC JUICE, DUODENAL JUICE, AND BILE OF THE DOG AS MEASURED BY ITS RADIOACTIVE ISOTOPE (Zn(65))
title_full THE ELIMINATION OF ADMINISTERED ZINC IN PANCREATIC JUICE, DUODENAL JUICE, AND BILE OF THE DOG AS MEASURED BY ITS RADIOACTIVE ISOTOPE (Zn(65))
title_fullStr THE ELIMINATION OF ADMINISTERED ZINC IN PANCREATIC JUICE, DUODENAL JUICE, AND BILE OF THE DOG AS MEASURED BY ITS RADIOACTIVE ISOTOPE (Zn(65))
title_full_unstemmed THE ELIMINATION OF ADMINISTERED ZINC IN PANCREATIC JUICE, DUODENAL JUICE, AND BILE OF THE DOG AS MEASURED BY ITS RADIOACTIVE ISOTOPE (Zn(65))
title_short THE ELIMINATION OF ADMINISTERED ZINC IN PANCREATIC JUICE, DUODENAL JUICE, AND BILE OF THE DOG AS MEASURED BY ITS RADIOACTIVE ISOTOPE (Zn(65))
title_sort elimination of administered zinc in pancreatic juice, duodenal juice, and bile of the dog as measured by its radioactive isotope (zn(65))
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135328/
https://www.ncbi.nlm.nih.gov/pubmed/19871318
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