ANTIGENIC RELATIONSHIP OF BRITISH SWINE INFLUENZA STRAINS TO STANDARD HUMAN AND SWINE INFLUENZA VIRUSES : THE USE OF CHICKEN AND FERRET ANTISERA IN RED CELL AGGLUTINATION

The antigenic relationships of Type A (PR 8, WS) and Type B (Lee) human strains and the Shope and British (Cambridge, North Ireland) swine strains were studied by specific antiserum inhibition of chicken red cell agglutination by the influenza virus. The Cambridge and North Ireland strains were foun...

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Detalles Bibliográficos
Autores principales: Hudson, N. Paul, Sigel, M. Michael, Markham, F. S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1943
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135355/
https://www.ncbi.nlm.nih.gov/pubmed/19871297
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author Hudson, N. Paul
Sigel, M. Michael
Markham, F. S.
author_facet Hudson, N. Paul
Sigel, M. Michael
Markham, F. S.
author_sort Hudson, N. Paul
collection PubMed
description The antigenic relationships of Type A (PR 8, WS) and Type B (Lee) human strains and the Shope and British (Cambridge, North Ireland) swine strains were studied by specific antiserum inhibition of chicken red cell agglutination by the influenza virus. The Cambridge and North Ireland strains were found to be closely related to the Type A strains and differentiated from the Shope virus. The distinctive antigenicity of the Lee strain of Type B was confirmed. Specific antibodies were developed in chickens following single intraperitoneal injections of influenza virus. Inhibition tests yielded results, in the antigenic analysis of the influenza viruses examined, comparable to those obtained with ferret antisera. Specific inhibition of hemagglutination by influenza virus proved an effective method for the study of strain relationships.
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spelling pubmed-21353552008-04-18 ANTIGENIC RELATIONSHIP OF BRITISH SWINE INFLUENZA STRAINS TO STANDARD HUMAN AND SWINE INFLUENZA VIRUSES : THE USE OF CHICKEN AND FERRET ANTISERA IN RED CELL AGGLUTINATION Hudson, N. Paul Sigel, M. Michael Markham, F. S. J Exp Med Article The antigenic relationships of Type A (PR 8, WS) and Type B (Lee) human strains and the Shope and British (Cambridge, North Ireland) swine strains were studied by specific antiserum inhibition of chicken red cell agglutination by the influenza virus. The Cambridge and North Ireland strains were found to be closely related to the Type A strains and differentiated from the Shope virus. The distinctive antigenicity of the Lee strain of Type B was confirmed. Specific antibodies were developed in chickens following single intraperitoneal injections of influenza virus. Inhibition tests yielded results, in the antigenic analysis of the influenza viruses examined, comparable to those obtained with ferret antisera. Specific inhibition of hemagglutination by influenza virus proved an effective method for the study of strain relationships. The Rockefeller University Press 1943-05-01 /pmc/articles/PMC2135355/ /pubmed/19871297 Text en Copyright © Copyright, 1943, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Hudson, N. Paul
Sigel, M. Michael
Markham, F. S.
ANTIGENIC RELATIONSHIP OF BRITISH SWINE INFLUENZA STRAINS TO STANDARD HUMAN AND SWINE INFLUENZA VIRUSES : THE USE OF CHICKEN AND FERRET ANTISERA IN RED CELL AGGLUTINATION
title ANTIGENIC RELATIONSHIP OF BRITISH SWINE INFLUENZA STRAINS TO STANDARD HUMAN AND SWINE INFLUENZA VIRUSES : THE USE OF CHICKEN AND FERRET ANTISERA IN RED CELL AGGLUTINATION
title_full ANTIGENIC RELATIONSHIP OF BRITISH SWINE INFLUENZA STRAINS TO STANDARD HUMAN AND SWINE INFLUENZA VIRUSES : THE USE OF CHICKEN AND FERRET ANTISERA IN RED CELL AGGLUTINATION
title_fullStr ANTIGENIC RELATIONSHIP OF BRITISH SWINE INFLUENZA STRAINS TO STANDARD HUMAN AND SWINE INFLUENZA VIRUSES : THE USE OF CHICKEN AND FERRET ANTISERA IN RED CELL AGGLUTINATION
title_full_unstemmed ANTIGENIC RELATIONSHIP OF BRITISH SWINE INFLUENZA STRAINS TO STANDARD HUMAN AND SWINE INFLUENZA VIRUSES : THE USE OF CHICKEN AND FERRET ANTISERA IN RED CELL AGGLUTINATION
title_short ANTIGENIC RELATIONSHIP OF BRITISH SWINE INFLUENZA STRAINS TO STANDARD HUMAN AND SWINE INFLUENZA VIRUSES : THE USE OF CHICKEN AND FERRET ANTISERA IN RED CELL AGGLUTINATION
title_sort antigenic relationship of british swine influenza strains to standard human and swine influenza viruses : the use of chicken and ferret antisera in red cell agglutination
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135355/
https://www.ncbi.nlm.nih.gov/pubmed/19871297
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AT sigelmmichael antigenicrelationshipofbritishswineinfluenzastrainstostandardhumanandswineinfluenzavirusestheuseofchickenandferretantiserainredcellagglutination
AT markhamfs antigenicrelationshipofbritishswineinfluenzastrainstostandardhumanandswineinfluenzavirusestheuseofchickenandferretantiserainredcellagglutination

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