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PRODUCTION OF A SCURVY-LIKE CONDITION BY FEEDING OF A COMPOUND STRUCTURALLY RELATED TO ASCORBIC ACID
The feeding of glucoascorbic acid, an analog of ascorbic acid, to mice and cotton rats caused the production of a condition exhibiting many of the changes characteristic of scurvy as seen in susceptible species. The condition was not prevented or cured by ascorbic acid, but was cured by removal of t...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1943
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135414/ https://www.ncbi.nlm.nih.gov/pubmed/19871333 |
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author | Woolley, D. W. Krampitz, L. O. |
author_facet | Woolley, D. W. Krampitz, L. O. |
author_sort | Woolley, D. W. |
collection | PubMed |
description | The feeding of glucoascorbic acid, an analog of ascorbic acid, to mice and cotton rats caused the production of a condition exhibiting many of the changes characteristic of scurvy as seen in susceptible species. The condition was not prevented or cured by ascorbic acid, but was cured by removal of the glucoascorbic acid from the ration. The condition was produced in mice fed a highly purified ration. It was not produced in mice fed a natural ration. The presence of a substance in certain plant products which prevented the production of the condition was demonstrated. |
format | Text |
id | pubmed-2135414 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1943 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21354142008-04-18 PRODUCTION OF A SCURVY-LIKE CONDITION BY FEEDING OF A COMPOUND STRUCTURALLY RELATED TO ASCORBIC ACID Woolley, D. W. Krampitz, L. O. J Exp Med Article The feeding of glucoascorbic acid, an analog of ascorbic acid, to mice and cotton rats caused the production of a condition exhibiting many of the changes characteristic of scurvy as seen in susceptible species. The condition was not prevented or cured by ascorbic acid, but was cured by removal of the glucoascorbic acid from the ration. The condition was produced in mice fed a highly purified ration. It was not produced in mice fed a natural ration. The presence of a substance in certain plant products which prevented the production of the condition was demonstrated. The Rockefeller University Press 1943-11-01 /pmc/articles/PMC2135414/ /pubmed/19871333 Text en Copyright © Copyright, 1943, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Woolley, D. W. Krampitz, L. O. PRODUCTION OF A SCURVY-LIKE CONDITION BY FEEDING OF A COMPOUND STRUCTURALLY RELATED TO ASCORBIC ACID |
title | PRODUCTION OF A SCURVY-LIKE CONDITION BY FEEDING OF A COMPOUND STRUCTURALLY RELATED TO ASCORBIC ACID |
title_full | PRODUCTION OF A SCURVY-LIKE CONDITION BY FEEDING OF A COMPOUND STRUCTURALLY RELATED TO ASCORBIC ACID |
title_fullStr | PRODUCTION OF A SCURVY-LIKE CONDITION BY FEEDING OF A COMPOUND STRUCTURALLY RELATED TO ASCORBIC ACID |
title_full_unstemmed | PRODUCTION OF A SCURVY-LIKE CONDITION BY FEEDING OF A COMPOUND STRUCTURALLY RELATED TO ASCORBIC ACID |
title_short | PRODUCTION OF A SCURVY-LIKE CONDITION BY FEEDING OF A COMPOUND STRUCTURALLY RELATED TO ASCORBIC ACID |
title_sort | production of a scurvy-like condition by feeding of a compound structurally related to ascorbic acid |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135414/ https://www.ncbi.nlm.nih.gov/pubmed/19871333 |
work_keys_str_mv | AT woolleydw productionofascurvylikeconditionbyfeedingofacompoundstructurallyrelatedtoascorbicacid AT krampitzlo productionofascurvylikeconditionbyfeedingofacompoundstructurallyrelatedtoascorbicacid |